Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits

A Caspi, AR Hariri, A Holmes, R Uher… - American journal of …, 2010 - Am Psychiatric Assoc
Evidence of marked variability in response among people exposed to the same
environmental risk implies that individual differences in genetic susceptibility might be at …

Genetics of human prefrontal function

G Winterer, D Goldman - Brain Research Reviews, 2003 - Elsevier
Evolution of the prefrontal cortex was an essential precursor to civilization. During the past
decade, it became increasingly obvious that human prefrontal function is under substantial …

Sound level dependence of the primary auditory cortex: Simultaneous measurement with 61-channel EEG and fMRI

C Mulert, L Jäger, S Propp, S Karch, S Störmann… - Neuroimage, 2005 - Elsevier
Sound level dependence has been investigated for years with event-related potentials
(ERP). A serotonergic modulation of the sound level dependence only of the primary …

Association of the G1947A COMT (Val108/158Met) gene polymorphism with prefrontal P300 during information processing

J Gallinat, M Bajbouj, T Sander, P Schlattmann, K Xu… - Biological …, 2003 - Elsevier
BACKGROUND: A common functional polymorphism, G1947A, of the catechol-O-
methyltransferase (COMT) enzyme has gained interest in schizophrenia research because …

Prediction of treatment response in major depression: integration of concepts

C Mulert, G Juckel, M Brunnmeier, S Karch… - Journal of affective …, 2007 - Elsevier
BACKGROUND: Two promising approaches have been introduced for the prediction of
treatment response in major depression: one concept is based on the activity in the rostral …

Childhood autism and auditory system abnormalities

M Hitoglou, A Ververi, A Antoniadis, DI Zafeiriou - Pediatric neurology, 2010 - Elsevier
Hearing disorders are common among children with autism, ranging from peripheral and
sensorineural hearing deficit or loss to auditory hypersensitivity with bizarre reactions to …

Randomized placebo-controlled trial of a selective serotonin reuptake inhibitor in the treatment of nondepressed tinnitus subjects

SK Robinson, ES Viirre, KA Bailey… - Psychosomatic …, 2005 - journals.lww.com
Objective: To assess the efficacy of a selective serotonin reuptake inhibitor (paroxetine) for
relief of tinnitus. Design: One hundred twenty tinnitus sufferers participated in a randomized …

Antidepressant therapy in tinnitus

SK Robinson, ES Viirre, MB Stein - Hearing research, 2007 - Elsevier
Objective: Review the literature on the co-morbidity of depression and anxiety with tinnitus.
Briefly consider proposed mechanisms by which antidepressants might be helpful for …

The loudness dependence of the auditory evoked potential (LDAEP) as an in vivo biomarker of central serotonergic function in humans: rationale, evaluation and …

BV O'neill, RJ Croft, PJ Nathan - … : Clinical and Experimental, 2008 - Wiley Online Library
Objectives The loudness dependence of the auditory evoked potential (LDAEP) has been
proposed as a valid means of non‐invasively assessing in vivo central serotonin (5 …

Serotonin transporter gene variation impacts innate fear processing: acoustic startle response and emotional startle

B Brocke, D Armbruster, J Muller, T Hensch… - Molecular …, 2006 - nature.com
Anxiety-related behaviors are closely linked to neural circuits relaying fear-specific
information to the amygdala. Many of these circuits, like those underlying processing of …