A current alternative for sustainable development through green chemistry is the
replacement of synthetic compounds with natural ones through the superior capitalization of …

Abstract A series of 11-substituted 9-hydroxy-3, 5, 10, 11-tetrahydro-2H-benzo [6, 7]
thiochromeno [2, 3-d][1, 3] thiazole-2, 5, 10-triones 3.1–3.13 were synthesized via hetero …

The sea cucumber Apostichopus japonicus has important nutritional and medicinal value.
Unfortunately, we know little of the source of active chemicals in this animal, but the plentiful …

Near-stoichiometric amounts of 18O2 and 17O2 were generated ex situ from endoperoxides
in a two-chamber glassware to oxidize various substrates. This strategy gave [* O2] …

Colorectal cancer (CRC) is estimated as the third most incident cancer and second in
mortality worldwide. Moreover, CRC metastasis reduces patients' survival rates. Thus, the …

In this study, a series of 2-and/or 3-substituted juglone derivatives were designed and
synthesized. Among them, 9, 18, 22, 30, and 31 showed stronger inhibition activity against …

Background Ferroptosis, a non-apoptotic form of cell death induced by accumulation of free
iron ions and lipid peroxidation, its importance for cancer treatment is gradually being …

Purinergic receptors are transmembrane proteins responsive to extracellular nucleotides
and are expressed by several cell types throughout the human body. Among all identified …

Chemotherapy remains the standard protocol for cancers, but the amount of
chemotherapeutic agents used for hepatocellular carcinoma (HCC) is still low. For this …

The study investigates the biological activity of spaced juglone dimers derived from the
reaction of juglone with dicarboxylic acid dichlorides of varying chain lengths. It builds upon …