[HTML][HTML] Plant-derived natural medicines for the management of osteoporosis: A comprehensive review of clinical trials

SM Karimi, M Bayat, R Rahimi - Journal of Traditional and Complementary …, 2024 - Elsevier
Background Osteoporosis is a chronic and systemic skeletal disease that is defined by low
bone mineral density (BMD) along with an increase in bone fragility and susceptibility to …

The effect of genistein aglycone on cancer and cancer risk: a review of in vitro, preclinical, and clinical studies

CK Taylor, RM Levy, JC Elliott, BP Burnett - Nutrition reviews, 2009 - academic.oup.com
In Asian epidemiological studies, health benefits, including reduced incidence of breast and
prostate cancers, are attributed to soy food and isoflavone consumption. The recent …

Regular supplementation with resveratrol improves bone mineral density in postmenopausal women: a randomized, placebo‐controlled trial

RHX Wong, JJ Thaung Zaw, CJ Xian… - Journal of Bone and …, 2020 - academic.oup.com
Resveratrol, a naturally occurring polyphenol in red grapes and berries, can act as a
phytoestrogen. It has been shown to improve both systemic and cerebral circulatory …

Breast safety and efficacy of genistein aglycone for postmenopausal bone loss: a follow-up study

H Marini, A Bitto, D Altavilla, BP Burnett… - The Journal of …, 2008 - academic.oup.com
Context: Genistein aglycone improves bone metabolism in women. However, questions
about the long-term safety of genistein on breast as well as its continued efficacy still remain …

Molecular signaling mechanisms behind polyphenol-induced bone anabolism

E Torre - Phytochemistry Reviews, 2017 - Springer
For millennia, in the different cultures all over the world, plants have been extensively used
as a source of therapeutic agents with wide-ranging medicinal applications, thus becoming …

Soy isoflavones and bone health: Focus on the RANKL/RANK/OPG pathway

SH Hooshiar, M Tobeiha… - BioMed research …, 2022 - Wiley Online Library
Bone remodels via resorption and formation, two phenomena that continuously occur in
bone turnover. The RANKL/RANK/OPG pathway is one of the several mechanisms that …

Effect of soy isoflavone extract supplements on bone mineral density in menopausal women: meta-analysis of randomized controlled trials

K Taku, MK Melby, J Takebayashi… - Asia Pacific journal …, 2010 - search.informit.org
This study was conducted to clarify the effect of ingesting soy isoflavone extracts (not soy
protein or foods containing isoflavones) on bone mineral density (BMD) in menopausal …

The role of soy isoflavones in the prevention of bone loss in postmenopausal women: A systematic review with meta-analysis of randomized controlled trials

A Barańska, W Kanadys, M Bogdan, E Stępień… - Journal of Clinical …, 2022 - mdpi.com
The aim of the report was to determine the effects of soy isoflavones on lumbar spine,
femoral neck, and total hip bone mineral density (BMD) in menopausal women. MEDLINE …

Changes in parameters of bone metabolism in postmenopausal women following a 12-month intervention period using dairy products enriched with calcium, vitamin …

S Kanellakis, G Moschonis, R Tenta… - Calcified tissue …, 2012 - Springer
The objective of the present study was to examine the effect of dairy products enriched with
calcium, vitamin D 3, and phylloquinone (vitamin K 1) or menaquinone-7 (vitamin K 2) on …

Obesity and metabolic comorbidities: environmental diseases?

C Lubrano, G Genovesi, P Specchia… - Oxidative medicine …, 2013 - Wiley Online Library
Obesity and metabolic comorbidities represent increasing health problems. Endocrine
disrupting compounds (EDCs) are exogenous agents that change endocrine function and …