HIV infection

LG Bekker, C Beyrer, N Mgodi, SR Lewin… - Nature Reviews …, 2023 - nature.com
The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …

Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

Diversity and evolution of the animal virome

E Harvey, EC Holmes - Nature Reviews Microbiology, 2022 - nature.com
The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses

SY Fung, KS Yuen, ZW Ye, CP Chan… - Emerging microbes & …, 2020 - Taylor & Francis
ABSTRACT World Health Organization has declared the ongoing outbreak of coronavirus
disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus …

MXene-based aptasensors: Advances, challenges, and prospects

S Ullah, F Shahzad, B Qiu, X Fang, A Ammar… - Progress in Materials …, 2022 - Elsevier
The combination of 2D MXenes with high affinity aptamers has resulted in the development
of innovative aptasensing approaches for food/water safety and clinical diagnosis. Aptamers …

Biodiversity loss, emerging pathogens and human health risks

DS Schmeller, F Courchamp, G Killeen - Biodiversity and conservation, 2020 - Springer
Outbreaks of emerging infectious diseases are occurring with increasing frequency and
consequences, including wildlife diseases and zoonoses. Those have potentially long …

Zoonotic spillover: Understanding basic aspects for better prevention

JH Ellwanger, JAB Chies - Genetics and Molecular Biology, 2021 - SciELO Brasil
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

Approved antiviral drugs over the past 50 years

E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

HIV subtype diversity worldwide

N Bbosa, P Kaleebu, D Ssemwanga - Current Opinion in HIV and …, 2019 - journals.lww.com
The dynamic change in HIV subtype distribution presents future challenges for diagnosis,
treatment and vaccine design and development. An increase in recombinant viruses …

HIV infection: epidemiology, pathogenesis, treatment, and prevention

G Maartens, C Celum, SR Lewin - The Lancet, 2014 - thelancet.com
HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …