Development of the human placenta

MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

Next-generation DNA sequencing methods

ER Mardis - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Recent scientific discoveries that resulted from the application of next-generation DNA
sequencing technologies highlight the striking impact of these massively parallel platforms …

The complete sequence of a human genome

S Nurk, S Koren, A Rhie, M Rautiainen, AV Bzikadze… - Science, 2022 - science.org
Since its initial release in 2000, the human reference genome has covered only the
euchromatic fraction of the genome, leaving important heterochromatic regions unfinished …

[图书][B] Mendelian randomization: methods for causal inference using genetic variants

S Burgess, SG Thompson - 2021 - books.google.com
Mendelian Randomization: Methods For Causal Inference Using Genetic Variants provides
thorough coverage of the methods and practical elements of Mendelian randomization …

[图书][B] Mendelian randomization: methods for using genetic variants in causal estimation

S Burgess, SG Thompson - 2015 - books.google.com
Presents the Terminology and Methods of Mendelian Randomization for Epidemiological
StudiesMendelian randomization uses genetic instrumental variables to make inferences …

The UCSC genome browser and associated tools

RM Kuhn, D Haussler, WJ Kent - Briefings in bioinformatics, 2013 - academic.oup.com
Abstract The UCSC Genome Browser (http://genome. ucsc. edu) is a graphical viewer for
genomic data now in its 13th year. Since the early days of the Human Genome Project, it has …

Principles of RNA processing from analysis of enhanced CLIP maps for 150 RNA binding proteins

EL Van Nostrand, GA Pratt, BA Yee, EC Wheeler… - Genome biology, 2020 - Springer
Background A critical step in uncovering rules of RNA processing is to study the in vivo
regulatory networks of RNA binding proteins (RBPs). Crosslinking and immunoprecipitation …

Initial sequencing and analysis of the human genome

US DOE Joint Genome Institute: Hawkins Trevor 4 … - Nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

The human genome browser at UCSC

WJ Kent, CW Sugnet, TS Furey, KM Roskin… - Genome …, 2002 - genome.cshlp.org
As vertebrate genome sequences near completion and research refocuses to their analysis,
the issue of effective genome annotation display becomes critical. A mature web tool for …

Finishing the euchromatic sequence of the human genome

International Human Genome Sequencing Consortium - Nature, 2004 - nature.com
The sequence of the human genome encodes the genetic instructions for human
physiology, as well as rich information about human evolution. In 2001, the International …