Failed Back Surgery Syndrome: No Longer a Surgeon's Defeat—A Narrative Review

G Miękisiak - Medicina, 2023 - mdpi.com
The introduction of the term Persistent Spinal Pain Syndrome (PSPS-T1/2), replacing the
older term Failed Back Surgery Syndrome (FBSS), has significantly influenced our approach …

[HTML][HTML] Sensitivity of the fasciae to sex hormone levels: Modulation of collagen-I, collagen-III and fibrillin production

C Fede, C Pirri, C Fan, G Albertin, A Porzionato… - PLoS …, 2019 - journals.plos.org
Although it is now recognized that women suffer from myofascial pain to a greater extent
than men, and that the muscular fasciae can respond to hormonal stimuli, thanks to the …

Spinal Adhesive Arachnoidopathy, the Disorder More Than Simply Adhesive Arachnoiditis: A Comprehensive Systematic Review of 510 Cases

W Zhang, Z Liu, K Wang, L Zhang, S Liu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Spinal adhesive arachnoidopathy (SAA) is a chronic pathology associated with
persistent inflammatory responses in the arachnoid. Adhesive arachnoiditis (AA) is one of …

[HTML][HTML] Continuous release of mefloquine featured in electrospun fiber membranes alleviates epidural fibrosis and aids in sensory neurological function after lumbar …

Z Yue, B Hu, Z Chen, G Zheng, Y Wang, C Yang… - Materials Today Bio, 2022 - Elsevier
Recurrent low back pain after spinal surgeries, such as lumbar laminectomy, is a major
complication of excessive epidural fibrosis. Although multiple preclinical and clinical …

Metformin attenuates post‐epidural fibrosis by inhibiting the TGF‐β1/Smad3 and HMGB1/TLR4 signaling pathways

Z Song, T Wu, J Sun, H Wang, F Hua… - Journal of cellular …, 2021 - Wiley Online Library
Excessive post‐epidural fibrosis is a common cause of recurrent back pain after spinal
surgery. Though various treatment methods have been conducted, the safe and effective …

[HTML][HTML] Impact of radial extracorporeal shock wave therapy in post-laminectomy epidural fibrosis in a rat model

B Haberal, EK Şimşek, K Akpınar… - Joint diseases and …, 2021 - ncbi.nlm.nih.gov
Objectives This study aims to investigate the effect of radial extracorporeal shock wave
therapy (rESWT) treatment in the prevention of epidural fibrosis after laminectomy in rats …

The role of hemostatic devices in neurosurgery. A systematic review

GR Giammalva, L Brunasso, R Costanzo… - Journal of Clinical …, 2021 - Elsevier
Hemostasis represents a fundamental step in every surgical procedure. During
neurosurgical procedures, proper and robust hemostasis into confined spaces can …

Analysis of pain markers and epidural fibrosis caused by repeated spinal surgery in Sprague–Dawley rats

M Quan, WH Hwang, JH Kim, YY Kim - BMC Musculoskeletal Disorders, 2021 - Springer
Background Epidural fibrosis is one of the aetiologies of pain following a spinal revision
surgery. It is reported that the specific members of the mitogen–activated protein kinases …

The preventive effect of curcumin on the experimental rat epidural fibrosis model

C Demirel, D Turkoz, IM Yazicioglu, C Cokluk - World Neurosurgery, 2021 - Elsevier
Objective The aim of the study was to evaluate the effect of systemically administrated
curcumin on the prevention of peridural fibrotic tissue and adhesion formation in a rat …

Pharmacotherapies to prevent epidural fibrosis after laminectomy: a systematic review of in vitro and in vivo animal models

V Ganesh, Y Kancherla, CM Igram, AJ Pugely… - The Spine Journal, 2023 - Elsevier
ABSTRACT BACKGROUND CONTEXT Excessive production of epidural fibrosis in the
nerve root can be a pain source after laminectomy. Pharmacotherapy is a minimally invasive …