Autophagy is a conserved process in which the cytosolic materials are degraded and
eventually recycled for cellular metabolism to maintain homeostasis. The dichotomous role …

Rational design of multifunctional nanomedicines has revolutionized the therapeutic efficacy
of cancers. Herein, we have constructed the functional nucleic acids (FNAs)-engineered …

Pyroptosis is an inflammatory form of programmed cell death that holds great promise in
cancer therapy. However, autophagy as the crucial pyroptosis checkpoint and the self …

Despite the challenges posed by drug resistance and side effects, chemotherapy remains a
pivotal strategy in cancer treatment. A key issue in this context is macroautophagy …

Cancer cells are addictive to exogenous methionine to gear toward tumor proliferation.
Meanwhile, they can replenish methionine pool from polyamine metabolism through a …

Autophagy captures damaged or dysfunctional proteins and organelles through the
lysosomal pathway to achieve proper cellular homeostasis. Autophagy possesses distinct …

Hypoxic tumors present a significant challenge in cancer therapy due to their ability to
adaptation in low-oxygen environments, which supports tumor survival and resistance to …

The tumor microenvironment, characterized by hypoxia, supports the efficacy of anaerobic
bacteria like attenuated S. typhimurium in cancer therapies. These bacteria target and …

Nanomedicine based drug delivery platforms provide an interesting avenue to explore for
the future of cancer treatment. Here we discuss the barriers for drug delivery in cancer …

Nanofibers are one of the most important morphologies of molecular self‐assemblies, the
formation of which relies on the diverse intermolecular interactions of fibrous‐forming units …