TMEM16A ion channel: A novel target for cancer treatment

S Li, Z Wang, R Geng, W Zhang, H Wan, X Kang… - Life Sciences, 2023 - Elsevier
Cancer draws attention owing to the high morbidity and mortality. It is urgent to develop safe
and effective cancer therapeutics. The calcium-activated chloride channel TMEM16A is …

[HTML][HTML] Integrating Artificial Intelligence for Advancing Multiple-Cancer Early Detection via Serum Biomarkers: A Narrative Review

HY Wang, WY Lin, C Zhou, ZA Yang, S Kalpana… - Cancers, 2024 - mdpi.com
The concept and policies of multicancer early detection (MCED) have gained significant
attention from governments worldwide in recent years. In the era of burgeoning artificial …

Comparison between three different techniques for the detection of EGFR mutations in liquid biopsies of patients with advanced stage lung adenocarcinoma

M Casula, M Pisano, P Paliogiannis… - International Journal of …, 2023 - mdpi.com
Oncogenic mutations in the EGFR gene are targets of tyrosine kinase inhibitors (TKIs) in
lung adenocarcinoma (LC) patients, and their search is mandatory to make decisions on …

Deciphering KDM8 dysregulation and CpG methylation in hepatocellular carcinoma using multi-omics and machine learning

F Ahmed, NK Mishra, OA Alghamdi, MI Khan… - …, 2024 - Taylor & Francis
Aim: This study investigates the altered expression and CpG methylation patterns of histone
demethylase KDM8 in hepatocellular carcinoma (HCC), aiming to uncover insights and …

The cancer glycocode as a family of diagnostic biomarkers, exemplified by tumor-associated gangliosides

A Nejatie, SS Yee, A Jeter, HU Saragovi - Frontiers in Oncology, 2023 - frontiersin.org
One unexploited family of cancer biomarkers comprise glycoproteins, carbohydrates, and
glycolipids (the Tumor Glycocode). A class of glycolipid cancer biomarkers, the tumor …

Advancements in Cancer Research: 3D Models, Single‐Cell, and Live‐Cell Techniques for Better Insights

F Carnevali, S Forciniti, V Onesto… - Advanced …, 2024 - Wiley Online Library
The present review provides a comprehensive overview of the current state of in vitro cancer
studies, focusing on recent advancements and ongoing in cell culture models and analyses …

[HTML][HTML] Effects of opioid drugs on immune function in cancer patients

Y Li, L Sun, Q Zhou, AJ Lee, L Wang, R Zhang… - Biomedicine & …, 2024 - Elsevier
Opioid receptor agonists are often used when cancer patients undergo surgery or analgesic
treatment. As analgesics in clinical care, opioids can provide intraoperative or to chronic …

[HTML][HTML] Modulatory Effect of Cucurbitacin D from Elaeocarpus hainanensis on ZNF217 Oncogene Expression in NPM-Mutated Acute Myeloid Leukemia

S Adorisio, A Fierabracci, BT Cham, VD Hoang… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: The expression of oncogene zinc-finger protein 217 (ZNF217) has
been reported to play a central role in cancer development, resistance, and recurrence …

Functional analysis and validation of oncodrive gene AP3S1 in ovarian cancer through filtering of mutation data from whole-exome sequencing

D Kong, Y Wu, Q Liu, C Huang, T Wang… - European Journal of …, 2024 - Springer
Background High-grade serous ovarian carcinoma (HGSOC) is the most aggressive and
prevalent subtype of ovarian cancer and accounts for a significant portion of ovarian cancer …

[PDF][PDF] Cucurbitacin D from Elaeocarpus hainanensis Modulates ZNF217 in NPM-Mutated Acute Myeloid Leukemia

S Adorisio, A Fierabracci, BT Cham, HD Vudinh… - 2024 - preprints.org
The expression of the oncogene zinc-finger protein 217 (ZNF217) has been reported to play
a central role in cancer development, resistance, and recurrence. Therefore, targeting …