The metal centres in metalloenzymes and molecular catalysts are responsible for the rearrangement of atoms and electrons during complex chemical reactions, and they enable …
The DIALS project is a collaboration between Diamond Light Source, Lawrence Berkeley National Laboratory and CCP4 to develop a new software suite for the analysis of …
Light-induced oxidation of water by photosystem II (PS II) in plants, algae and cyanobacteria has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi …
I Ishigami, RG Sierra, Z Su, A Peck, C Wang… - Nature …, 2023 - nature.com
Cytochrome c oxidase (C c O) is an essential enzyme in mitochondrial and bacterial respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …
AM Orville - Current Opinion in Structural Biology, 2020 - Elsevier
Highlights•Time-resolved serial femtosecond crystallography (tr-SFX) probes structure and function in each sample.•X-ray free electron lasers (XFELS) provide atomic and electronic …
HN Chapman - Annual review of biochemistry, 2019 - annualreviews.org
X-ray free-electron lasers provide femtosecond-duration pulses of hard X-rays with a peak brightness approximately one billion times greater than is available at synchrotron radiation …
X-ray free electron lasers (XFELs) have the potential to revolutionize macromolecular structural biology due to the unique combination of spatial coherence, extreme peak …
ML Grünbein, G Nass Kovacs - Acta Crystallographica Section D …, 2019 - journals.iucr.org
The high peak brilliance and femtosecond pulse duration of X-ray free-electron lasers (XFELs) provide new scientific opportunities for experiments in physics, chemistry and …
J Mailliot, F Martin - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell entrance. Since viral genomes do not encode any components of the protein biosynthesis …