Serial femtosecond crystallography

TRM Barends, B Stauch, V Cherezov… - Nature reviews Methods …, 2022 - nature.com
With the advent of X-ray free-electron lasers (XFELs), new, high-throughput serial
crystallography techniques for macromolecular structure determination have emerged …

Using X-ray free-electron lasers for spectroscopy of molecular catalysts and metalloenzymes

U Bergmann, J Kern, RW Schoenlein, P Wernet… - Nature Reviews …, 2021 - nature.com
The metal centres in metalloenzymes and molecular catalysts are responsible for the
rearrangement of atoms and electrons during complex chemical reactions, and they enable …

[HTML][HTML] DIALS: implementation and evaluation of a new integration package

G Winter, DG Waterman, JM Parkhurst… - … Section D: Structural …, 2018 - scripts.iucr.org
The DIALS project is a collaboration between Diamond Light Source, Lawrence Berkeley
National Laboratory and CCP4 to develop a new software suite for the analysis of …

Structure of photosystem II and substrate binding at room temperature

ID Young, M Ibrahim, R Chatterjee, S Gul, FD Fuller… - Nature, 2016 - nature.com
Light-induced oxidation of water by photosystem II (PS II) in plants, algae and cyanobacteria
has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi …

Structural insights into functional properties of the oxidized form of cytochrome c oxidase

I Ishigami, RG Sierra, Z Su, A Peck, C Wang… - Nature …, 2023 - nature.com
Cytochrome c oxidase (C c O) is an essential enzyme in mitochondrial and bacterial
respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …

[HTML][HTML] Recent results in time resolved serial femtosecond crystallography at XFELs

AM Orville - Current Opinion in Structural Biology, 2020 - Elsevier
Highlights•Time-resolved serial femtosecond crystallography (tr-SFX) probes structure and
function in each sample.•X-ray free electron lasers (XFELS) provide atomic and electronic …

X-ray free-electron lasers for the structure and dynamics of macromolecules

HN Chapman - Annual review of biochemistry, 2019 - annualreviews.org
X-ray free-electron lasers provide femtosecond-duration pulses of hard X-rays with a peak
brightness approximately one billion times greater than is available at synchrotron radiation …

A bright future for serial femtosecond crystallography with XFELs

LC Johansson, B Stauch, A Ishchenko… - Trends in biochemical …, 2017 - cell.com
X-ray free electron lasers (XFELs) have the potential to revolutionize macromolecular
structural biology due to the unique combination of spatial coherence, extreme peak …

[PDF][PDF] Sample delivery for serial crystallography at free-electron lasers and synchrotrons

ML Grünbein, G Nass Kovacs - Acta Crystallographica Section D …, 2019 - journals.iucr.org
The high peak brilliance and femtosecond pulse duration of X-ray free-electron lasers
(XFELs) provide new scientific opportunities for experiments in physics, chemistry and …

Viral internal ribosomal entry sites: four classes for one goal

J Mailliot, F Martin - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell
entrance. Since viral genomes do not encode any components of the protein biosynthesis …