[HTML][HTML] Targeting the “sweet spot” in septic shock–A perspective on the endothelial glycocalyx regulating proteins Heparanase-1 and-2
T Pape, AM Hunkemöller, P Kümpers, H Haller… - Matrix biology plus, 2021 - Elsevier
Sepsis is a life-threatening syndrome caused by a pathological host response to an infection
that eventually, if uncontrolled, leads to septic shock and ultimately, death. In sepsis, a …
that eventually, if uncontrolled, leads to septic shock and ultimately, death. In sepsis, a …
Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling
Y Kiyan, S Tkachuk, K Kurselis, N Shushakova… - Scientific reports, 2019 - nature.com
The endothelial glycocalyx and its regulated shedding are important to vascular health.
Endo-β-D-glucuronidase heparanase-1 (HPSE1) is the only enzyme that can shed heparan …
Endo-β-D-glucuronidase heparanase-1 (HPSE1) is the only enzyme that can shed heparan …
The good and bad sides of heparanase-1 and heparanase-2
In this chapter, we will emphasize the importance of heparan sulfate proteoglycans (HSPG)
in controlling various physiological and pathological molecular mechanisms and discuss …
in controlling various physiological and pathological molecular mechanisms and discuss …
[PDF][PDF] Die Rolle von Heparanase 1 und Heparanase 2 in der Degradierung der endothelialen Glykokalyx beim septischen Schock
UC Hillebrand - 2023 - scholar.archive.org
In der vorliegenden Arbeit beschäftige ich mich mit den molekularen und zellulären
Mechanismen der Sepsis. Dabei wird vor allem auf die Rolle des Endothels und der …
Mechanismen der Sepsis. Dabei wird vor allem auf die Rolle des Endothels und der …
[PDF][PDF] Expression of cathepsin B in human hepatocellular carcinoma and its prognostic significance
L Qin, J Chen, J Wang, J Ye, H Tan, L Xu - Int J Clin Exp Pathol, 2016 - e-century.us
The objective of this study was to analyze the expression of cathepsin B (CTSB) and its
clinicopathological significance in patients with hepatocellular carcinoma (HCC). The …
clinicopathological significance in patients with hepatocellular carcinoma (HCC). The …
Heparanase modulation by Wingless/INT (Wnt)
Heparanase is an endo-beta-glucuronidase, the only enzyme in mammals capable of
cleaving heparan sulfate/heparin chains from proteoglycans. The oligosaccharides …
cleaving heparan sulfate/heparin chains from proteoglycans. The oligosaccharides …