Although instrumented nanoindentation testing has been used to characterize the
mechanical properties of materials since the 1970s, the vast majority of the research …

Publisher Summary This chapter focuses on the process related to the breakage of single
particles. Particle breakage in comminution and degradation processes is the result of a …

Nanoindentation is a technique for measuring the elastic modulus and hardness of small
amounts of materials. This method, which has been used extensively for characterizing …

Nanoindentation is applied to the two polymorphs of aspirin to examine and differentiate
their interaction anisotropy and shear instability. Aspirin provides an excellent test system for …

Crystals of voriconazole, an antifungal drug, are soft in nature, and this is disadvantageous
during compaction studies where pressure is applied on the solid. Crystal engineering is …

The phenomenon of particle interaction involved in pulmonary drug delivery belongs to a
wide variety of disciplines of particle technology, in particular, fluidization. This paper …

The nanoindentation technique has been employed to relate the mechanical properties of
saccharin single crystals with their internal structure. Indentations were performed on (100) …

Mechanical behavior of pharmaceutical crystals directly impacts the formulation
development and manufacturing of drug products. The understanding of crystal structure …

Production of iron ore pellets typically requires regrinding of the iron ore concentrates.
Although these concentrates are produced following close control of chemical composition …

The impact grinding behaviour of materials can be characterized by the two breakage
parameters fMat and xWm, min [Vogel and Peukert, Powder Technol. 129 (2003) 101–110] …