Myocilin is highly expressed in the trabecular meshwork (TM), which plays an important role
in the regulation of intraocular pressure (IOP). Myocilin abnormalities may cause dysfunction …

The idea that amyloid fibrils and other types of protein aggregates are toxic for cells has
been challenged by the discovery of a variety of functional aggregates. However, an …

As previously described by several authors, dental pulp stem cells (DPSCs), when
adequately stimulated, may acquire a neuronal-like phenotype acting as a favorable source …

Disulfide bonds play an important role in thiol‐based redox regulation. However, owing to
the lack of analytical tools, little is known about how local O2 mediates the reversible …

Ozonation was widely used before ultrafiltration processes, but its effect mechanism on
protein fouling is still controversial. Ozonation of bovine serum albumin (BSA) solutions was …

Amyloid‐like peptide nanofibrils (PNFs) are abundant in nature providing rich bioactivities
and playing both functional and pathological roles. The structural features responsible for …

Amyloid formation involves the conversion of soluble protein species to an aggregated state.
Amyloid fibrils of β-parvalbumin, a protein abundant in fish, act as an allergen but also inhibit …

The tumor suppressor p16 INK4A induces cell cycle arrest and senescence in response to
oncogenic transformation and is therefore frequently lost in cancer. p16 INK4A is also known …

Proteins can transform from their native state to a state having fibrillar aggregates
characterized by cross β sheet structure. The fibrillar aggregates are known as amyloid and …

Protein aggregation appears to originate from partially unfolded conformations that are
sampled through stochastic fluctuations of the native protein. It has been a challenge to …