Ankyrin proteins act as molecular scaffolds and play an essential role in regulating cellular
functions. Recent evidence has implicated the ANK3 gene, encoding ankyrin-G, in bipolar …

Over the last decade, a large variety of alterations of the Contactin Associated Protein 2
(CNTNAP2) gene, encoding Caspr2, have been identified in several neuronal disorders …

The Sigma-1 Receptor (Sigmar1) is a stress-activated chaperone and a promising target for
pharmacological modulation due to its ability to induce multiple cellular responses. Yet, it is …

BACKGROUND Women demonstrate a memory advantage when cognitively healthy yet
lose this advantage to men in Alzheimer's disease. However, the genetic underpinnings of …

Despite good adherence to supervised endurance exercise training (EET), some individuals
experience no or little improvement in peripheral insulin sensitivity. The genetic and …

We report a consanguineous Arab family with 3 affected siblings who display a disorder of
global developmental delay, learning difficulties, facial dysmorphism, hearing impairments …

Females comprise two-thirds of Alzheimer's disease (AD) cases, and females have a twofold
increased lifetime risk for AD as compared to males. Furthermore, females have a higher AD …

Alzheimer's disease (AD) is the most frequent neurodegenerative disease with an
increasing prevalence in industrialized, ageing populations. AD susceptibility has an …

Kanser, sanayileşmenin artması ile dünya çapında önemli bir halk sağlığı problemi haline
gelmiştir. Kolorektal kanser (KRK) Dünya ve Türkiye genelinde kanserler arasında 3. sırada …