Aims Ferulic acid is a polyphenolic compound with proven anticancer properties, but it
suffers from low solubility and bioavailability. In the current work, polymeric and lipidic …

Cancer ranks among the most life‐threatening diseases worldwide and is continuously
affecting all age groups. Consequently, many research studies are being carried out to …

Three series of novel 1-aryl-3-(4-methylsulfonylphenyl) pyrazole derivatives were
synthesized, characterized by several spectroscopic techniques, and investigated as …

NSAIDs are the most famous anti-inflammatory drugs and are mainly classified into two
groups, the non-selective NSAIDs that inhibit both COX-1 and COX-2 enzymes with side …

Abstract Synthesis of 5-(4-methoxyphenyl)-7-phenyl-2-(pyridin-2-yl) imidazo [1, 2-a] pyridine-
8-carbonitrile has been carried out by the reaction between 1-(pyridin-2-yl) ethanone and 2 …

Herein, the design, synthesis and mechanistic study of five series of imidazo [1, 2-a]
pyridines 8a-d, 9a-f, 11a-c, 12a-d and 14a-d as anticancer agents were discussed. The …

Introduction: Imidazo [1, 2-a] pyridine derivatives with diverse pharmacological properties
and curcumin, as a potential natural anti-inflammatory compound, are promising compounds …

Nitrogen ring junction heterocycles play a crucial role in synthetic organic chemistry due to
their remarkable activity. The fused nitrogen ring junction compounds are abundant in …

Cancer is a multifaceted disease with high mortality rates, and current treatments face
challenges such as chemoresistance and tumor adaptation. Since Virchow reported the first …

Data on the main types of biological activity of condensed pyridine derivatives with a
bridgehead nitrogen atom, including the structures of the most promising molecules and the …