Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Adolescent binge drinking is a major risk factor for psychiatric disorders later in life including
alcohol use disorder. Adolescent alcohol exposure induces epigenetic reprogramming at …

Excessive drinking damages the central nervous system of individuals and can even cause
alcohol use disorder (AUD). AUD is regulated by both genetic and environmental factors …

Alcohol consumption is one of the leading causes of death worldwide. Adolescence is a
critical period of structural and functional maturation of the brain. Adolescent alcohol use can …

Positive effects of alcohol drinking such as anxiolysis and euphoria appear to be a crucial
factor in the initiation and maintenance of alcohol use disorder (AUD). However, the …

During adolescence, the brain is highly susceptible to alcohol-induced damage and
subsequent neuroimmune responses, effects which may enhance development of an …

Adolescents are particularly vulnerable to initiation of the use of substances harmful to
health, and its increase is cause for concern. The objective of this study was to analyze the …

Addiction is a chronically relapsing neuropsychiatric disease that occurs in some, but not all,
individuals who use substances of abuse. Relatively little is known about the mechanisms …

Background Adolescence and early-adulthood are vulnerable developmental periods
during which binge drinking can have long-lasting effects on brain function. However, little is …

Alcohol use disorder (AUD) is a worldwide problem. Unfortunately, the molecular
mechanisms of alcohol misuse are still poorly understood, therefore successful therapeutic …