Cell organelles as targets of mammalian cadmium toxicity

WK Lee, F Thévenod - Archives of toxicology, 2020 - Springer
Ever increasing environmental presence of cadmium as a consequence of industrial
activities is considered a health hazard and is closely linked to deteriorating global health …

The actin cytoskeleton in hair bundle development and hearing loss

J Park, JE Bird - Hearing research, 2023 - Elsevier
Inner ear hair cells assemble mechanosensitive hair bundles on their apical surface that
transduce sounds and accelerations. Each hair bundle is comprised of∼ 100 individual …

Microbially induced calcium precipitation driven by denitrification: Performance, metabolites, and molecular mechanisms

Z Wang, J Su, A Ali, Z Gao, R Zhang, Y Li… - Journal of Environmental …, 2023 - Elsevier
Microbially induced calcium precipitation (MICP) driven by denitrification has attracted
extensive attention due to its application potential in nitrate removal from calcium-rich …

Surface-associated antigen induces permeabilization of primary mouse B-cells and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

FY Maeda, JJH van Haaren, DB Langley, D Christ… - Elife, 2021 - elifesciences.org
Abstract B-cell receptor (BCR)-mediated antigen internalization and presentation are
essential for humoral memory immune responses. Antigen encountered by B-cells is often …

Signaling enzymes and ion channels being modulated by the actin cytoskeleton at the plasma membrane

F Vasilev, Y Ezhova, JT Chun - International journal of molecular sciences, 2021 - mdpi.com
A cell should deal with the changing external environment or the neighboring cells.
Inevitably, the cell surface receives and transduces a number of signals to produce apt …

Getting cells into shape by calcium-dependent actin cross-linking proteins

F Lehne, S Bogdan - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
The actin cytoskeleton represents a highly dynamic filament system providing cell structure
and mechanical forces to drive a variety of cellular processes. The dynamics of the actin …

Design and applications of small molecular probes for calcium detection

Roopa, N Kumar, M Kumar… - Chemistry–An Asian …, 2019 - Wiley Online Library
The physiological significance of calcium ions such as the role in cellular signalling, cell
growth, etc. have driven the development of methods to detect and monitor the level of Ca2+ …

Insights and perspectives on calcium channel functions in the cockpit of cancerous space invaders

S Leverrier-Penna, O Destaing, A Penna - Cell Calcium, 2020 - Elsevier
Abstract Development of metastasis causes the most serious clinical consequences of
cancer and is responsible for over 90% of cancer-related deaths. Hence, a better …

[HTML][HTML] The dynamic nature of the K-Ras/calmodulin complex can be altered by oncogenic mutations

H Abdelkarim, N Leschinsky, H Jang… - Current Opinion in …, 2021 - Elsevier
Oncogenic mutant K-Ras promotes cancer cell proliferation, migration, invasion, and
survival by assembling signaling complexes. To date, the functional and structural roles of K …

Developmental brain abnormalities and acute encephalopathy in a patient with myopathy with extrapyramidal signs secondary to pathogenic variants in MICU1

KM Wilton, JA Morales‐Rosado, D Selcen… - JIMD …, 2020 - Wiley Online Library
Mitochondria play a variety of roles in the cell, far beyond their widely recognized role in ATP
generation. One such role is the regulation and sequestration of calcium, which is done with …