Health issues in Hispanic/Latino youth.

CR Isasi, D Rastogi, K Molina - Journal of Latina/o psychology, 2016 - psycnet.apa.org
Este artículo de revisión se centra en la obesidad, el asma y la salud mental, problemas de
salud importantes que afectan a jóvenes hispanos. También se discute la carga de estas …

Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci

S Stender, J Kozlitina, BG Nordestgaard… - Nature …, 2017 - nature.com
Complex traits arise from the interplay between genetic and environmental factors. The
actions of these factors usually appear to be additive, and few compelling examples of gene …

PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease

M Krawczyk, P Portincasa… - Seminars in liver …, 2013 - thieme-connect.com
Nonalcoholic fatty liver disease is one of the most common hepatic disorders worldwide.
Given the high-calorie nutrition of children and adults, nonalcoholic fatty liver disease …

[PDF][PDF] The expression of PNPLA3 polymorphism could be the key for severe liver disease in NAFLD in Hispanic population

LA Martínez, E Larrieta, JJ Calva… - Annals of …, 2018 - medigraphic.com
ABSTRACT Background. Background. Nonalcoholic fatty liver disease (NAFLD)
encompasses: fatty liver (SS), steatohepatitis (NASH) with or without fibrosis and cirrhosis …

PNPLA3 variant M148 causes resistance to starvation‐mediated lipid droplet autophagy in human hepatocytes

F Negoita, J Blomdahl, S Wasserstrom… - Journal of cellular …, 2019 - Wiley Online Library
The mechanism of how patatin‐like phospholipase domain‐containing protein 3 (PNPLA3)
variant M148 is associated with increased risk of development of hepatic steatosis is still …

New perspectives on genetic prediction for pediatric metabolic associated fatty liver disease

YC Lin, CC Wu, YH Ni - Frontiers in Pediatrics, 2020 - frontiersin.org
Non-alcoholic or recently re-defined metabolic associated fatty liver disease (MAFLD), a
spectrum of progressive hepatic disease, has become a public health issue in obese …

[HTML][HTML] A natural history study of paediatric non-alcoholic fatty liver disease over 10 years

L Draijer, M Voorhoeve, M Troelstra, A Holleboom… - JHEP Reports, 2023 - Elsevier
Background & Aims The long-term outcome of paediatric non-alcoholic fatty liver disease
(NAFLD) has not been well established. Between 2008 and 2012, an unselected cohort of …

A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity

P Leon-Mimila, J Vega-Badillo… - … and molecular pathology, 2015 - Elsevier
Background and aims Genome-wide association studies have identified single nucleotide
polymorphisms (SNPs) near/in PNPLA3, NCAN, LYPLAL1, PPP1R3B, and GCKR genes …

Circulating triacylglycerol signatures in nonalcoholic fatty liver disease associated with the I148M variant in PNPLA3 and with obesity

J Hyysalo, P Gopalacharyulu, H Bian, T Hyötyläinen… - Diabetes, 2014 - Am Diabetes Assoc
We examined whether relative concentrations of circulating triacylglycerols (TAGs) between
carriers compared with noncarriers of PNPLA3I148M gene variant display deficiency of …

Personalized medicine and nutrition in hepatology for preventing chronic liver disease in Mexico

A Panduro, S Roman, IM Mariscal-Martinez… - Frontiers in …, 2024 - frontiersin.org
Chronic liver disease is a global health issue. Patients with chronic liver disease require a
fresh approach that focuses on the genetic and environmental factors that contribute to …