A contemporary review on Data Preprocessing (DP) practice strategy in ATR-FTIR spectrum

LC Lee, CY Liong, AA Jemain - Chemometrics and Intelligent Laboratory …, 2017 - Elsevier
ATR-FTIR spectroscopy in the combination with chemometrics has been practiced over the
past decades. Works presented in numerous disciplines provide ample empirical evidence …

[HTML][HTML] Mammalian systems biotechnology reveals global cellular adaptations in a recombinant CHO cell line

FNK Yusufi, M Lakshmanan, YS Ho, BLW Loo… - Cell systems, 2017 - cell.com
Effective development of host cells for therapeutic protein production is hampered by the
poor characterization of cellular transfection. Here, we employed a multi-omics-based …

An LC–MS-based lipidomics pre-processing framework underpins rapid hypothesis generation towards CHO systems biotechnology

HC Yeo, S Chen, YS Ho, DY Lee - Metabolomics, 2018 - Springer
Introduction Given a raw LC–MS dataset, it is often required to rapidly generate initial
hypotheses, in conjunction with other 'omics' datasets, without time-consuming lipid …

Toward integrated multi‐omics analysis for improving CHO cell bioprocessing

KS Ang, J Hong, M Lakshmanan… - Cell culture engineering …, 2019 - Wiley Online Library
Chinese hamster ovary (CHO) cells are the most popular mammalian host cells used in the
production of human‐compatible recombinant drugs because of their capability to perform …

Computational tools for the processing and analysis of time-course metabolomic data

MJ Rusilowicz - 2016 - etheses.whiterose.ac.uk
Modern, high-throughput techniques for the acquisition of metabolomic data, combined with
an increase in computational power, have provided not only the need for, but also the …

Systems Biotechnology Tools for Guiding the Development of Cho Cell Bioprocessing

YH Chuan - 2020 - search.proquest.com
Chinese hamster ovary (CHO) cells are commonly used to produce biopharmaceuticals.
While a variety of empirical approaches have been used to improve the bioprocess, they are …

Machine Learning in Metabolic Engineering

S Mitra - Machine Learning and IoT, 2018 - taylorfrancis.com
Bioprocess industries aim to employ bacteria for the large-scale production of a particular
compound. The bacteria, however, simply grow in numbers to maintain their population, and …