Organ-on-a-chip technology, a promising three-dimensional (3D) dynamic culture method,
ensures accurate and efficient cell culture and has great potential for replacing animal …

Simple Summary CXCL12 and its receptors have been extensively studied in cancer,
including their influence on cancer stem cells (CSCs) and their niche. This intensive …

Triple-negative breast cancer (TNBC) exhibits the poorest outcomes among breast cancer
subtypes due to the high heterogeneity and a lasting scarcity of effectual treatments …

Cancer stem cells (CSCs), a subpopulation of cancer cells endowed with self-renewal,
tumorigenicity, pluripotency, chemoresistance, differentiation, invasive ability, and plasticity …

Cancer stem cells (CSCs) are a small subpopulation of cancer cells with capabilities of self-
renewal, differentiation, and tumorigenicity, and play a critical role in driving tumor …

In humans, various sites like cannabinoid receptors (CBR) having a binding affinity with
cannabinoids are distributed on the surface of different cell types, where endocannabinoids …

Cancer stem cells (CSCs) are a small proportion of cancer cells with high tumorigenic
activity, self-renewal ability, and multilineage differentiation potential. Standard anti-tumor …

Cancer is a major disease that endangers human health. Cancer drug resistance and
relapse are the two main causes contributing to cancer treatment failure. Cancer stem cells …

Introduction: NPC2 is well known as a player for cholesterol transport. However, the
biological role of NPC2 in cancer development and therapy is far from clear. Methods: Here …

Central nervous system (CNS) tumors are a variety of distinct neoplasms that present
multiple challenges in terms of treatment and prognosis. Glioblastoma, the most common …