Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …

In the past decades, various nanomaterials with unique properties have been explored for
bioapplications. Meanwhile, aptamers, generated from the systematic evolution of ligands by …

Achieving controlled and accurate delivery of photosensitizers (PSs) into tumor sites is a
major challenge in conventional photodynamic therapy (PDT). Aptamer is a short …

The ability to self-assemble one-dimensional DNA building blocks into two-and three-
dimensional nanostructures via DNA/RNA nanotechnology has led to broad applications in …

We describe a comprehensive protocol for the preparation of multifunctional DNA
nanostructures termed nanoflowers (NFs), which are self-assembled from long DNA building …

Specific interactions between ligands and receptors on cell surface play an important role in
the cell biological process. Nucleic acid aptamers as commonly used ligands enable …

Herein, we report on the design of a programmable DNA ribbon using long‐chain DNA
molecules with a user‐defined repetitive padlock sequence. The DNA ribbon can be further …

Nucleic acid aptamers generated through an in vitro selection are currently extensively
applied as very valuable biomolecular tools thanks to their prominent advantages. Diversity …

Poor efficacy and off-target systemic toxicity are major problems associated with current
chemotherapeutic approaches to treat cancer. We developed a new form of polyvalent …

The last two decades have witnessed the development and application of nucleic acid
aptamers in a variety of fields, including target analysis, disease therapy, and molecular and …