Does BRAF V600E mutation affect recurrence rate of ameloblastomas? Systematic review and meta‐analysis

AV Martins‐de‐Barros, CCG Silva… - Journal of Oral …, 2023 - Wiley Online Library
Objective The objective of this systematic review with meta‐analysis was to critically
evaluate the available data on the association of the BRAF V600E mutation and recurrence …

Genetic factors in the pathogenesis of ameloblastoma, dentigerous cyst and odontogenic keratocyst

S Ghafouri-Fard, S Atarbashi-Moghadam, M Taheri - Gene, 2021 - Elsevier
Abstract Ameloblastoma (AB), dentigerous cyst (DC) and Odontogenic keratocyst (OKC) are
odontogenic lesions with propensity to malignant transformation or local invasion. The …

BRAF V600E Mutation in Ameloblastoma: A Systematic Review and Meta-Analysis

MN Mamat@ Yusof, ES Ch'ng… - Cancers, 2022 - mdpi.com
Simple Summary Ameloblastoma is a benign odontogenic tumour, and the patient always
presents at a later stage when the tumour is already in an aggressive state. The finding of …

Identification of BRAF V600E mutation in odontogenic tumors by high-performance MALDI-TOF analysis

L Togni, A Zizzi, R Mazzucchelli, A Santarelli… - International Journal of …, 2022 - nature.com
Odontogenic tumors are rare lesions with unknown etiopathogenesis. Most of them are
benign, but local aggressiveness, infiltrative potential, and high recurrence rate characterize …

Identification of key biomarkers related to epithelial‐mesenchymal transition and immune infiltration in ameloblastoma using integrated bioinformatics analysis

Z Zhang, Y Peng, J Dang, X Liu, D Zhu, Y Zhang… - Oral …, 2023 - Wiley Online Library
Objective This study aimed to elucidate the underlying mechanisms of ameloblastoma (AM)
through integrated bioinformatics analysis. Methods We downloaded two microarrays of …

Inhibition of VEGFR2 and EGFR signaling cooperatively suppresses the proliferation of oral squamous cell carcinoma

M Onda, A Ota, K Ito, T Ono, S Karnan, M Kato… - Cancer …, 2023 - Wiley Online Library
Background Epidermal growth factor receptor (EGFR) is frequently overexpressed in oral
squamous cell carcinoma (OSCC), and EGFR‐targeting therapeutics have been widely …

Analyses of transcriptomics cell signalling for pre-screening applications in the integrated approach for testing and assessment of non-genotoxic carcinogens

Y Oku, F Madia, P Lau, M Paparella… - International Journal of …, 2022 - mdpi.com
With recent rapid advancement of methodological tools, mechanistic understanding of
biological processes leading to carcinogenesis is expanding. New approach methodologies …

[HTML][HTML] Molecular biology exploration and targeted therapy strategy of Ameloblastoma

Y Lu, X Zhang, X Li - Archives of Oral Biology, 2022 - Elsevier
Objective This article aims to systematically and comprehensively discuss molecular biology-
related progress and targeted therapeutic strategies for ameloblastoma, which are expected …

Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma

G Xiong, N Xie, M Nie, R Ling, B Yun, J Xie… - International Journal of …, 2024 - nature.com
Ameloblastoma is a benign tumor characterized by locally invasive phenotypes, leading to
facial bone destruction and a high recurrence rate. However, the mechanisms governing …

Potential biomarkers and signaling pathways associated with the pathogenesis of primary ameloblastoma: a systems biology approach

Z Bayat, A Mirzaeian… - International Journal of …, 2022 - Wiley Online Library
Objective. Ameloblastoma is a benign odontogenic tumor that may lead to ameloblastic
carcinoma. This study aimed to determine potential signaling pathways and biological …