Current standard-of-care (SOC) therapy for breast cancer includes targeted therapies such
as endocrine therapy for estrogen receptor-alpha (ERα) positive; anti-HER2 monoclonal …

Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

The hormone estrogen (E2) binds the estrogen receptor to promote transcription of E2-
responsive genes in the breast and other tissues. E2 also has links to genomic instability …

Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient
requirements, metabolism and response to nutritional and dietary interventions. Indeed …

New approach methodologies (NAMs) that efficiently provide information about chemical
hazard without using whole animals are needed to accelerate the pace of chemical risk …

Estradiol (E2) is a major hormone controlling women fertility, in particular folliculogenesis.
This steroid, which is locally produced by granulosa cells (GC) within ovarian follicles …

Objective This study was designed to evaluate the effects of equol and resveratrol
supplementation on health-related quality of life (HRQoL) in otherwise healthy menopausal …

The potential benefit of soy isoflavones in breast cancer chemoprevention, as suggested by
epidemiological studies, has aroused the interest of numerous scientists for over twenty …

Cutaneous melanoma is an aggressive tumor; its incidence has been reported to increase
fast in the past decades. Melanoma is a heterogeneous tumor, with most patients harboring …

Background Natural estrogen decline leads to vasomotor symptoms (VMS). Hormone
therapy alleviates symptoms but increases cancer risk. Effective treatments against VMS …