3D bioprinting is an additive manufacturing technique that recapitulates the native
architecture of tissues. This is accomplished through the precise deposition of cell …

Fibrosis represents a major global disease burden, yet a potent antifibrotic compound is still
not in sight. Part of the explanation for this situation is the difficulties that both academic …

Background—The purpose of this study was to determine whether patients with heart failure
and a preserved ejection fraction (HFpEF) have an increase in passive myocardial stiffness …

Clinical evidence links arterial calcification and cardiovascular risk. Finite-element modelling
of the stress distribution within atherosclerotic plaques has suggested that subcellular …

Collagen quantification has long been relevant to biomedical research and clinical practice
to characterize tissues and determine disease states. The hydroxyproline assay, while a …

Matrix metalloproteinase-9 (MMP-9) is prominently overexpressed after myocardial
infarction (MI). We tested the hypothesis that mice with targeted deletion of MMP9 have less …

Staining of collagens by Sirius Red, a standard histological procedure, was applied to
quantify collagen synthesis in human osteoblast-like cell cultures in situ. After morphological …

The biocompatibility of titania/hydroxyapatite (TiO2/HA) composite coatings, at different ratio
obtained by sol–gel process, were investigated studying the behaviour of human MG63 …

We examine the relationships of three variables (projected area, migration speed, and
traction force) at various type I collagen surface densities in a population of fibroblasts. We …

The initial contact of osteoblasts with implant surfaces is an important event for
osseointegration of implants. Osseointegration of Ti6Al4V may be improved by precoating of …