Esophageal cancer is the eighth most common type of cancer worldwide and constitutes the
sixth leading cause of cancer deaths. It is characterized by its high mortality rate, poor …

Abstract Purpose of the Review Esophageal cancer is the sixth most common cause of
cancer death globally. Squamous cell carcinoma of the esophagus (ESCC) is the …

The poor prognosis and rising incidence of esophageal cancer highlight the need for
improved detection and prediction methods that are essential prior to treatment. Esophageal …

Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical
functions in the body. There are markedly conflicting findings in the literature regarding the …

A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a
subject of recent interest, as its role in detoxifying aldehydes that accumulate through …

Approximately half of the world's 500,000 new oesophageal squamous-cell carcinoma
(ESCC) cases each year occur in China. Here, we show whole-genome sequencing of DNA …

DNA damage plays a major role in various pathophysiological conditions including
carcinogenesis, aging, inflammation, diabetes and neurodegenerative diseases. Oxidative …

Dietary and other environmental factors induce epigenetic alterations which may have
important consequences for cancer development. This chapter summarizes current …

In retrospective studies of esophageal cancer (EC), cigarettes and hookah smoking, nass
use (a chewing tobacco product), opium consumption, hot tea drinking, poor oral health, low …

Alcohol is a major risk factor for oesophageal squamous cell carcinoma (OSCC), the most
prevalent histological subtype of oesophageal cancer (OC) worldwide. The metabolism of …