Organocatalyzed asymmetric α-oxidation, α-aminoxylation and α-amination of carbonyl compounds
T Vilaivan, W Bhanthumnavin - Molecules, 2010 - mdpi.com
Organocatalytic asymmetric α-oxidation and amination reactions of carbonyl compounds are
highly useful synthetic methodologies, especially in generating chiral building blocks that …
highly useful synthetic methodologies, especially in generating chiral building blocks that …
Organocatalysis: trends of drug synthesis in medicinal chemistry
Background: The continuous increase in challenges associated with the effective treatment
of life threatening diseases influences the development of drug therapies with suitable …
of life threatening diseases influences the development of drug therapies with suitable …
Aminooxylation Horner–Wadsworth–Emmons Sequence for the Synthesis of Enantioenriched γ-Functionalized Vinyl Sulfones
W Doherty, P Evans - The Journal of Organic Chemistry, 2016 - ACS Publications
An operationally simple protocol for the synthesis of γ-hydroxy vinyl sulfones has been
developed using a proline-based aldehyde aminooxylation, followed by a vinyl sulfone …
developed using a proline-based aldehyde aminooxylation, followed by a vinyl sulfone …
Recent advances on the organocatalyzed enantioselective α-heterofunctionalization of carbonyl compounds
G Guillena, D J. Ramon - Current Organic Chemistry, 2011 - benthamdirect.com
This review covers literature on organocatalyzed enantioselective α-heterofunctionalization
of carbonyl compounds from 2006 to 2009. In this review, we will consider those reactions in …
of carbonyl compounds from 2006 to 2009. In this review, we will consider those reactions in …
A facile enantioselective synthesis of (S)-N-(5-chlorothiophene-2-sulfonyl)-β, β-diethylalaninol via proline-catalyzed asymmetric α-aminooxylation and α-amination of …
V Rawat, PV Chouthaiwale, VB Chavan… - Tetrahedron …, 2010 - Elsevier
A high-yielding enantioselective synthesis of the bioactive (S)-N-(5-chlorothiophene-2-
sulfonyl)-β, β-diethylalaninol (1), a Notch-1-sparing γ-secretase inhibitor metabolite (with …
sulfonyl)-β, β-diethylalaninol (1), a Notch-1-sparing γ-secretase inhibitor metabolite (with …
Practical synthesis of trans-dihydroxybutyrolactols as chiral C 4 building blocks and their application to the synthesis of polyhydroxylated alkaloids
Practical syntheses of trans-dihydroxybutyrolactols 2a, 2b and 2c from inexpensive chiral
pool compounds L-ascorbic, D-and L-tartaric acid have been achieved on a multigram …
pool compounds L-ascorbic, D-and L-tartaric acid have been achieved on a multigram …
Polymer-immobilized α, α-bis [bis-3, 5-(trifluoromethyl) phenyl] prolinol silyl ether: synthesis and application in the asymmetric α-amination of aldehydes
AA Guryev, MV Anokhin, AD Averin… - Mendeleev …, 2015 - mathnet.ru
Polymer-immobilized α,α-bis[bis-3,5-(trifluoromethyl)phenyl]prolinol silyl ether: synthesis and
application in the asymmetric Page 1 Mendeleev Commun., 2015, 25, 410–411 – 410 …
application in the asymmetric Page 1 Mendeleev Commun., 2015, 25, 410–411 – 410 …
Pd-catalyzed reductive cleavage of NN bond in dibenzyl-1-alkylhydrazine-1, 2-dicarboxylates with PMHS: application to a formal enantioselective synthesis of (R) …
An environmentally benign approach involving Pd-catalyzed reductive Nsingle bondN bond
cleavage in dibenzyl-1-alkylhydrazine-1, 2-dicarboxylates leading to the synthesis of N-(tert …
cleavage in dibenzyl-1-alkylhydrazine-1, 2-dicarboxylates leading to the synthesis of N-(tert …
Studies Towards the Synthesis of (+)-and (–)-Anisomycin and Their Analogues
S Ajay, AK Shaw - Synthesis, 2018 - thieme-connect.com
Anisomycin shows potent biological activity and it has attracted much attention since its
isolation in 1954, with around 13 total syntheses and 20 formal syntheses, and also two …
isolation in 1954, with around 13 total syntheses and 20 formal syntheses, and also two …
Synthetic drives for useful drug molecules through organocatalytic methods
Abstract The treatment<? index value=" treatment"?> of various pathological conditions in
human beings involves the use of safe and efficacious drug<? index value=" drug"?> …
human beings involves the use of safe and efficacious drug<? index value=" drug"?> …