Monitoring the periodic diurnal variations in cortisol from small volume samples of serum or
saliva is of great interest, due to the regulatory role of cortisol within various physiological …

Due to the increase in the number of cancer patients, because of environmental parameters,
high stress, low immunity, etc., there is an urgent need to develop cost-effective sensors for …

Neuropeptides are vital to the transmission and modulation of neurological signals, with
Neuropeptide Y (NPY) and Orexin A (OXA) offering diagnostic information on stress …

Heterogeneous immunoassays usually require long incubation times to promote specific
target binding and several wash steps to eliminate non-specific binding. Hence, signal …

Thiol-gold (Au) conjugation is perhaps the most routinely applied surface chemistry
approach to immobilize receptors within Au-based molecular sensing platforms. However …

Mapping transcription factor (TF) binding sites along a DNA backbone is crucial in
understanding the regulatory circuits that control cellular processes. Here, we deployed a …

Fast detection of low-abundance protein remains a challenge because detection speed is
limited by analyte transport to the detection site of a biosensor. In this paper, we demonstrate …

BACKGROUND Biosensors are devices for sensing and detecting biomol ecules and
operate on the basis of electronic, electrochemi cal, optical, and mechanical detection …

Intracellular delivery of functional molecules such as proteins, transcription factors and DNA
is effective and promising in cell biology. However, existing transfection methods are often …

The biofunctionalization of nanoelectromechanical systems (NEMS) is critical for the
development of new classes of biosensors displaying improved performance and higher …