Advances in early breast cancer risk profiling: from histopathology to molecular technologies
Simple Summary Risk stratification for early breast cancer (BC) is extremely relevant for
tailoring clinical decisions but challenging due to the absence of comprehensive guidelines …
tailoring clinical decisions but challenging due to the absence of comprehensive guidelines …
Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice
Smoke from wildland fires has been shown to produce neuroinflammation in preclinical
models, characterized by neural infiltrations of neutrophils and monocytes, as well as altered …
models, characterized by neural infiltrations of neutrophils and monocytes, as well as altered …
Simultaneous quantitation and discovery (SQUAD) analysis: combining the best of targeted and untargeted mass spectrometry-based metabolomics
B Amer, RR Deshpande, SS Bird - Metabolites, 2023 - mdpi.com
Untargeted and targeted approaches are the traditional metabolomics workflows acquired
for a wider understanding of the metabolome under focus. Both approaches have their …
for a wider understanding of the metabolome under focus. Both approaches have their …
Technology and future of multi-cancer early detection
DA Milner Jr, JK Lennerz - Life, 2024 - mdpi.com
Cancer remains a significant global health challenge due to its high morbidity and mortality
rates. Early detection is essential for improving patient outcomes, yet current diagnostic …
rates. Early detection is essential for improving patient outcomes, yet current diagnostic …
Metabolomic profiles of metformin in breast cancer survivors: a pooled analysis of plasmas from two randomized placebo-controlled trials
Background Obesity is a major health concern for breast cancer survivors, being associated
with high recurrence and reduced efficacy during cancer treatment. Metformin treatment is …
with high recurrence and reduced efficacy during cancer treatment. Metformin treatment is …
Integrating bulk and single-cell RNA sequencing data reveals the relationship between intratumor microbiome signature and host metabolic heterogeneity in breast …
F Chen, J Yang, Y Guo, D Su, Y Sheng… - Frontiers in …, 2023 - frontiersin.org
Introduction Nowadays, it has been recognized that gut microbiome can indirectly modulate
cancer susceptibility or progression. However, whether intratumor microbes are parasitic …
cancer susceptibility or progression. However, whether intratumor microbes are parasitic …
E. coli Secretome Metabolically Modulates MDA-MB-231 Breast Cancer Cells' Energy Metabolism
Breast cancer (BC) is commonly diagnosed in women. BC cells are associated with altered
metabolism, which is essential to support their energetic requirements, cellular proliferation …
metabolism, which is essential to support their energetic requirements, cellular proliferation …
Serum untargeted metabolomics reveal metabolic alteration of non‐small cell lung cancer and refine disease detection
J Li, K Liu, Z Ji, Y Wang, T Yin, T Long, Y Shen… - Cancer …, 2023 - Wiley Online Library
This study was performed to characterize the metabolic alteration of non–small‐cell lung
cancer (NSCLC) and discover blood‐based metabolic biomarkers relevant to lung cancer …
cancer (NSCLC) and discover blood‐based metabolic biomarkers relevant to lung cancer …
The role of amino acids in the diagnosis, risk assessment, and treatment of breast cancer: A review
LV Bel'skaya, IA Gundyrev, DV Solomatin - Current Issues in Molecular …, 2023 - mdpi.com
This review summarizes the role of amino acids in the diagnosis, risk assessment, imaging,
and treatment of breast cancer. It was shown that the content of individual amino acids …
and treatment of breast cancer. It was shown that the content of individual amino acids …