Newly endocytosed integral cell surface proteins are typically either directed for degradation
or subjected to recycling back to the plasma membrane. The sorting of integral cell surface …

Phosphatidylserine (PtdSer), an essential constituent of eukaryotic membranes, is the most
abundant anionic phospholipid in the eukaryotic cell accounting for up to 10% of the total …

Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in
adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane …

Caveolae are small coated plasma membrane invaginations with diverse functions.
Caveolae undergo curvature changes. Yet, it is unclear which proteins regulate this process …

Endosomal transport is essential for cellular organization and compartmentalization and cell–
cell communication. Sorting endosomes provide a crossroads for various trafficking …

Caveolae are an abundant and characteristic surface feature of many vertebrate cells. The
uniform shape of caveolae is characterized by a bulb with consistent curvature connected to …

Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely
unexplored whether lysine acetylation regulates membrane protein function. Here, we use …

Background Membrane-bound intracellular organelles have characteristic shapes attributed
to different local membrane curvatures, and these attributes are conserved across species …

Synthetically replicating key biological processes requires the ability to puncture lipid bilayer
membranes and to remodel their shape. Recently developed artificial DNA nanopores are …

Caveolae introduce flask-shaped convolutions into the plasma membrane and help to
protect the plasma membrane from damage under stretch forces. The protein components …