Droplet-based microfluidics

T Moragues, D Arguijo, T Beneyton, C Modavi… - Nature Reviews …, 2023 - nature.com
Droplet-based microfluidic systems generate, manipulate and control sub-microlitre droplets
enclosed within an immiscible carrier fluid. Owing to a number of remarkable features, such …

Opportunities and challenges for biosensors and nanoscale analytical tools for pandemics: COVID-19

N Bhalla, Y Pan, Z Yang, AF Payam - ACS nano, 2020 - ACS Publications
Biosensors and nanoscale analytical tools have shown huge growth in literature in the past
20 years, with a large number of reports on the topic of 'ultrasensitive','cost-effective', and …

Recent advances in droplet microfluidics for single-cell analysis

Z Jiang, H Shi, X Tang, J Qin - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Single-cell manipulation and analysis is essential for studying many fundamental biological
processes and discovering cellular heterogeneity. Multi-parameter studies of intercellular …

Emerging droplet microfluidics

L Shang, Y Cheng, Y Zhao - Chemical reviews, 2017 - ACS Publications
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …

Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments

M Gantz, S Neun, EJ Medcalf, LD van Vliet… - Chemical …, 2023 - ACS Publications
Novel and improved biocatalysts are increasingly sourced from libraries via experimental
screening. The success of such campaigns is crucially dependent on the number of …

The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

DJ Collins, A Neild, A DeMello, AQ Liu, Y Ai - Lab on a Chip, 2015 - pubs.rsc.org
There is a recognized and growing need for rapid and efficient cell assays, where the size of
microfluidic devices lend themselves to the manipulation of cellular populations down to the …

Single-cell analysis tools for drug discovery and development

JR Heath, A Ribas, PS Mischel - Nature reviews Drug discovery, 2016 - nature.com
The genetic, functional or compositional heterogeneity of healthy and diseased tissues
presents major challenges in drug discovery and development. Such heterogeneity hinders …

Development and future of droplet microfluidics

L Nan, H Zhang, DA Weitz, HC Shum - Lab on a Chip, 2024 - pubs.rsc.org
Over the past two decades, advances in droplet-based microfluidics have facilitated new
approaches to process and analyze samples with unprecedented levels of precision and …

Design of pressure-driven microfluidic networks using electric circuit analogy

KW Oh, K Lee, B Ahn, EP Furlani - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …

Dynamics of microfluidic droplets

CN Baroud, F Gallaire, R Dangla - Lab on a Chip, 2010 - pubs.rsc.org
This critical review discusses the current understanding of the formation, transport, and
merging of drops in microfluidics. We focus on the physical ingredients which determine the …