Proteins and peptides as important modifiers of the polymer scaffolds for tissue engineering applications—a review

K Klimek, G Ginalska - Polymers, 2020 - mdpi.com
Polymer scaffolds constitute a very interesting strategy for tissue engineering. Even though
they are generally non-toxic, in some cases, they may not provide suitable support for cell …

Osteogenic potential of the growth factors and bioactive molecules in bone regeneration

B Safari, S Davaran, A Aghanejad - International journal of biological …, 2021 - Elsevier
The growing need for treatment of the impaired bone tissue has resulted in the quest for the
improvement of bone tissue regeneration strategies. Bone tissue engineering is trying to …

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function

G Santulli, A Wronska, K Uryu… - The Journal of …, 2014 - Am Soc Clin Investig
Drugs currently approved to coat stents used in percutaneous coronary interventions do not
discriminate between proliferating vascular smooth muscle cells (VSMCs) and endothelial …

3D bioprinting for vascularized tissue-engineered bone fabrication

F Xing, Z Xiang, PM Rommens, U Ritz - Materials, 2020 - mdpi.com
Vascularization in bone tissues is essential for the distribution of nutrients and oxygen, as
well as the removal of waste products. Fabrication of tissue-engineered bone constructs with …

Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis

D Zhao, D Xiao, M Liu, J Li, S Peng, Q He… - International Journal of …, 2022 - nature.com
The significant clinical feature of bisphosphonate-related osteonecrosis of the jaw (BRONJ)
is the exposure of the necrotic jaw. Other clinical manifestations include jaw pain, swelling …

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

LY Chan, S Gunasekera, ST Henriques… - Blood, The Journal …, 2011 - ashpublications.org
Fragments from the extracellular matrix proteins laminin and osteopontin and a sequence
from VEGF have potent proangiogenic activity despite their small size (< 10 residues) …

Highly angiogenic peptide nanofibers

VA Kumar, NL Taylor, S Shi, BK Wang, AA Jalan… - ACS …, 2015 - ACS Publications
Major limitations of current tissue regeneration approaches using artificial scaffolds are
fibrous encapsulation, lack of host cellular infiltration, unwanted immune responses, surface …

CaMK4 gene deletion induces hypertension

G Santulli, E Cipolletta, D Sorriento… - Journal of the …, 2012 - Am Heart Assoc
Background The expression of calcium/calmodulin‐dependent kinase IV (CaMKIV) was
hitherto thought to be confined to the nervous system. However, a recent genome‐wide …

Nanofibrous peptide hydrogel elicits angiogenesis and neurogenesis without drugs, proteins, or cells

AN Moore, TLL Silva, NC Carrejo, CAO Marmolejo… - Biomaterials, 2018 - Elsevier
The design of materials for regenerative medicine has focused on delivery of small molecule
drugs, proteins, and cells to help accelerate healing. Additionally, biomaterials have been …

MicroRNAs and endothelial (Dys) function

G Santulli - Journal of cellular physiology, 2016 - Wiley Online Library
Accumulating evidence indicates that microRNAs (miRs)—non‐coding RNAs that can
regulate gene expression via translational repression and/or post‐transcriptional …