An updated review of ciguatera fish poisoning: clinical, epidemiological, environmental, and public health management

MA Friedman, M Fernandez, LC Backer, RW Dickey… - Marine drugs, 2017 - mdpi.com
Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the
world. It causes substantial human health, social, and economic impacts. The illness …

Arsenic exposure and toxicology: a historical perspective

MF Hughes, BD Beck, Y Chen, AS Lewis… - Toxicological …, 2011 - academic.oup.com
The metalloid arsenic is a natural environmental contaminant to which humans are routinely
exposed in food, water, air, and soil. Arsenic has a long history of use as a homicidal agent …

Arsenic in the human food chain, biotransformation and toxicology–Review focusing on seafood arsenic

M Molin, SM Ulven, HM Meltzer, J Alexander - Journal of trace elements in …, 2015 - Elsevier
Fish and seafood are main contributors of arsenic (As) in the diet. The dominating arsenical
is the organoarsenical arsenobetaine (AB), found particularly in finfish. Algae, blue mussels …

Factors affecting arsenic methylation in arsenic-exposed humans: a systematic review and meta-analysis

H Shen, Q Niu, M Xu, D Rui, S Xu, G Feng… - International journal of …, 2016 - mdpi.com
Chronic arsenic exposure is a critical public health issue in many countries. The metabolism
of arsenic in vivo is complicated because it can be influenced by many factors. In the present …

AS3MT, GSTO, and PNP polymorphisms: impact on arsenic methylation and implications for disease susceptibility

R Antonelli, K Shao, DJ Thomas, R Sams II… - Environmental …, 2014 - Elsevier
Background Oral exposure to inorganic arsenic (iAs) is associated with adverse health
effects. Epidemiological studies suggest differences in susceptibility to these health effects …

Biomonitoring of humans exposed to arsenic, chromium, nickel, vanadium, and complex mixtures of metals by using the micronucleus test in lymphocytes

B Annangi, S Bonassi, R Marcos… - … Research/Reviews in …, 2016 - Elsevier
Various metals have demonstrated genotoxic and carcinogenic potential via different
mechanisms. Until now, biomonitoring and epidemiological studies have been carried out to …

Arsenic methyltransferase and methylation of inorganic arsenic

NK Roy, A Murphy, M Costa - Biomolecules, 2020 - mdpi.com
Arsenic occurs naturally in the environment, and exists predominantly as inorganic arsenite
(As (III) and arsenate As (V)). Arsenic contamination of drinking water has long been …

Nutritional influences on one-carbon metabolism: effects on arsenic methylation and toxicity

AK Bozack, R Saxena, MV Gamble - Annual review of nutrition, 2018 - annualreviews.org
Exposure to inorganic arsenic (InAs) via drinking water and/or food is a considerable
worldwide problem. Methylation of InAs generates monomethyl (MMAsIII+ V)-and dimethyl …

Metabolism of arsenic in human liver: the role of membrane transporters

Z Drobná, FS Walton, DS Paul, W Xing, DJ Thomas… - Archives of …, 2010 - Springer
Metabolism of inorganic arsenic (iAs) is one of the key factors determining the character of
adverse effects associated with exposure to iAs. Results of previous studies indicate that …

Structure of an As(III) S-Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation

AA Ajees, K Marapakala, C Packianathan… - Biochemistry, 2012 - ACS Publications
Enzymatic methylation of arsenic is a detoxification process in microorganisms but in
humans may activate the metalloid to more carcinogenic species. We describe the first …