Targeted covalent inhibitors (TCIs) are designed to bind poorly conserved amino acids by
means of reactive groups, the so-called warheads. Currently, targeting noncatalytic cysteine …

The perfluoroaryl⋯ aryl interaction, the most important subset of π-hole⋯ π bonding, refers to
the attractive stacking interaction between a perfluoroaryl group and an aryl group. In …

Antimicrobial peptides (AMPs) are host defense peptides, and unlike conventional
antibiotics, they possess potent broad spectrum activities and, induce little or no …

In this article, we report the design, synthesis, and characterization of a series of
cyclometalated iridium (III) polypyridine complexes containing a perfluorobiphenyl (PFBP) …

Fluorine aromatic hydrocarbons are ubiquitous optoelectronic functional materials and their
efficient synthetic methods are still the subject of rapid, ongoing development. Here, several …

A series of charged ABA triblock copolymers having sulfonated poly (phenylene sulfide
sulfone)(sPSS) as B-block and polystyrene (PS) as A-block have been successfully …

Linkers play major roles in conjugation chemistry toward the advancement of drug
discovery. Two different series of fluorinated linkers were introduced to the backbone of a …

Cysteine‐based perfluoroaromatic (hexafluorobenzene (HFB) and decafluorobiphenyl
(DFBP)) were synthesized and established as a chemoselective and available core to …

A series of cysteine-based perfluoroaromatic (hexafluorobenzene (I) and
decafluorobiphenyl (II) were synthesized and established as a chemoselective and …

Optochemical tools serve as potent instruments for the modulation of RNA-based processes.
This thesis introduces innovative development in the optochemical control of RNA splicing …