[HTML][HTML] Open source bioimage informatics tools for the analysis of DNA damage and associated biomarkers
J Schneider, R Weiss, M Ruhe, T Jung… - … of Laboratory and …, 2019 - jlpm.amegroups.org
DNA double-strand breaks (DSBs) are critical cellular lesions that represent a high risk for
genetic instability. DSBs initiate repair mechanisms by recruiting sensor proteins and …
genetic instability. DSBs initiate repair mechanisms by recruiting sensor proteins and …
From energy deposition of ionizing radiation to cell damage signaling: benchmarking simulations by measured yields of initial DNA damage after ion microbeam …
G Gonon, C Villagrasa, P Voisin… - Radiation …, 2019 - meridian.allenpress.com
Advances in accelerator technology, which have enabled conforming radiotherapy with
charged hadronic species, have brought benefits as well as potential new risks to patients …
charged hadronic species, have brought benefits as well as potential new risks to patients …
Evaluation of machine learning models for automatic detection of DNA double strand breaks after irradiation using a γH2AX foci assay
T Hohmann, J Kessler, D Vordermark, F Dehghani - PLoS One, 2020 - journals.plos.org
Ionizing radiation induces amongst other the most critical type of DNA damage: double-
strand breaks (DSBs). Efficient repair of such damage is crucial for cell survival and genomic …
strand breaks (DSBs). Efficient repair of such damage is crucial for cell survival and genomic …
A deep learning model (FociRad) for automated detection of γ-H2AX foci and radiation dose estimation
R Wanotayan, K Chousangsuntorn, P Petisiwaveth… - Scientific Reports, 2022 - nature.com
DNA double-strand breaks (DSBs) are the most lethal form of damage to cells from
irradiation. γ-H2AX (phosphorylated form of H2AX histone variant) has become one of the …
irradiation. γ-H2AX (phosphorylated form of H2AX histone variant) has become one of the …
Machine Learning Classification of DNA Damage Foci
M Benítez-Jones - 2023 - search.proquest.com
DNA damage foci are sensitive radiation markers reflective of DNA double-stranded break
formation. Manual focus counting, while prone to bias and time constraints, remains the most …
formation. Manual focus counting, while prone to bias and time constraints, remains the most …
[PDF][PDF] Regulation von zellulären Proteinnetzwerken nach Stresssignalen
RN Lengert - 2017 - tuprints.ulb.tu-darmstadt.de
Die Aufrechterhaltung des Stoffwechsels und der Funktion von lebenden Zellen erfordert
das Zusammenspiel komplexer Proteinnetzwerke. Diese ermöglichen der Zelle, variierende …
das Zusammenspiel komplexer Proteinnetzwerke. Diese ermöglichen der Zelle, variierende …
Investigative methods adapted to assess the biological properties of laser-driven protons
N Humble - 2014 - mediatum.ub.tum.de
Laser-driven technology offers the promise of a more affordable and compact source of
protons for radiotherapy. Prior to clinical implementation, the biological properties of laser …
protons for radiotherapy. Prior to clinical implementation, the biological properties of laser …
The effect of radiation on cellular ageing
RJ Sabin - 2012 - bura.brunel.ac.uk
Humans are exposed to low and moderate doses of ionising radiation (IR) from a range of
diagnostic and occupational sources which may lead to cellular effects including genomic …
diagnostic and occupational sources which may lead to cellular effects including genomic …