Highly sensitive and multiplexed protein measurements

L Cohen, DR Walt - Chemical reviews, 2018 - ACS Publications
Proteins are involved in many biological processes. Misfolded, truncated, or mutated
proteins as well as over-or underexpressed proteins have been implicated in many …

Porous silicon-based photonic biosensors: Current status and emerging applications

S Arshavsky-Graham, N Massad-Ivanir… - Analytical …, 2018 - ACS Publications
Since its first demonstration as a promising material for molecular detection two decades
ago, porous silicon (PSi) has become a commercially viable optical biosensor platform …

Aptamers vs. antibodies as capture probes in optical porous silicon biosensors

S Arshavsky-Graham, K Urmann, R Salama… - Analyst, 2020 - pubs.rsc.org
Over the past decade aptamers have emerged as a promising class of bioreceptors for
biosensing applications with significant advantages over conventional antibodies. However …

How antibody surface coverage on nanoparticles determines the activity and kinetics of antigen capturing for biosensing

B Saha, TH Evers, MWJ Prins - Analytical chemistry, 2014 - ACS Publications
The antigen-capturing activity of antibody-coated nanoparticles is very important for affinity-
based bioanalytical tools. In this paper, a comprehensive study is reported of the antigen …

Enhancing the performance of porous silicon biosensors: the interplay of nanostructure design and microfluidic integration

K Awawdeh, MA Buttkewitz, J Bahnemann… - Microsystems & …, 2024 - nature.com
This work presents the development and design of aptasensor employing porous silicon
(PSi) Fabry‒Pérot thin films that are suitable for use as optical transducers for the detection …

Photonic crystals in bioassays

Y Zhao, X Zhao, Z Gu - Advanced Functional Materials, 2010 - Wiley Online Library
Photonic crystal (PC) based bioassay techniques have many advantages in sensitive
biomolecular screening, label‐free detection, real‐time monitoring of enzyme activity, cell …

Biofunctionalization of multiplexed silicon photonic biosensors

LS Puumala, SM Grist, JM Morales, JR Bickford… - Biosensors, 2022 - mdpi.com
Silicon photonic (SiP) sensors offer a promising platform for robust and low-cost
decentralized diagnostics due to their high scalability, low limit of detection, and ability to …

Improving the sensitivity of nanofibrous membrane-based ELISA for on-site antibiotics detection

C Zhao, B Pan, M Wang, Y Si, AY Taha, G Liu… - ACS …, 2022 - ACS Publications
An ultrasensitive and portable colorimetric enzyme-linked immunosorbent assay (ELISA)
sensor for antibiotics was fabricated by immobilizing antibodies inside the largely porous …

Chemical surface modifications for the development of silicon-based label-free integrated optical (IO) biosensors: A review

MJ Bañuls, R Puchades, Á Maquieira - Analytica chimica acta, 2013 - Elsevier
Increasing interest has been paid to label-free biosensors in recent years. Among them,
refractive index (RI) optical biosensors enable high density and the chip-scale integration of …

Photoluminescence‐based sensing with porous silicon films, microparticles, and nanoparticles

MJ Sailor, EC Wu - Advanced Functional Materials, 2009 - Wiley Online Library
Here, chemical sensors made from porous Si are reviewed, with an emphasis on systems
that harness photoluminescence and related energy‐and charge‐transfer mechanisms …