Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

[HTML][HTML] Obesity, male infertility, and the sperm epigenome

JR Craig, TG Jenkins, DT Carrell, JM Hotaling - Fertility and sterility, 2017 - Elsevier
Obesity is a growing epidemic and a common problem among reproductive-age men that
can both cause and exacerbate male-factor infertility by means of endocrine abnormalities …

The environment and male reproduction: The effect of cadmium exposure on reproductive function and its implication in fertility

C De Angelis, M Galdiero, C Pivonello, C Salzano… - Reproductive …, 2017 - Elsevier
Cadmium is an environmental pollutant known as endocrine disruptor. Testis is particularly
susceptible to cadmium, and testis injury occurs at high but even low levels of exposure …

Epigenetic mechanisms of transmission of metabolic disease across generations

VM Sales, AC Ferguson-Smith, ME Patti - Cell metabolism, 2017 - cell.com
Both human and animal studies indicate that environmental exposures experienced during
early life can robustly influence risk for adult disease. Moreover, environmental exposures …

Epigenetics in male reproduction: effect of paternal diet on sperm quality and offspring health

U Schagdarsurengin, K Steger - Nature Reviews Urology, 2016 - nature.com
Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF/ICSI compared with children conceived …

G Lazaraviciute, M Kauser… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND Increasing numbers of children are being conceived by assisted
reproductive technology (ART). A number of studies have highlighted an altered epigenetic …

Paternal factors contributing to embryo quality

S Colaco, D Sakkas - Journal of assisted reproduction and genetics, 2018 - Springer
Purpose Advancing maternal and paternal age leads to a decrease in fertility, and hence,
many infertile couples opt for assisted reproductive technologies [ART] to achieve biological …

Epigenetics and male reproduction: the consequences of paternal lifestyle on fertility, embryo development, and children lifetime health

L Stuppia, M Franzago, P Ballerini, V Gatta… - Clinical …, 2015 - Springer
The correlation between epigenetics and human reproduction represents a very interesting
field of study, mainly due to the possible transgenerational effects related to epigenetic …

Epigenetics, spermatogenesis and male infertility

S Rajender, K Avery, A Agarwal - Mutation Research/Reviews in Mutation …, 2011 - Elsevier
Epigenetic modifications characterized by DNA methylation, histone modifications, and
chromatin remodeling are important regulators in a number of biological processes …

The preconception environment and sperm epigenetics

C Marcho, OA Oluwayiose, JR Pilsner - Andrology, 2020 - Wiley Online Library
Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …