Obesity has become one of the main threats to health worldwide and therefore gained
increasing clinical and economic significance as well as scientific attention. General adipose …

Adipose tissue (AT) is a highly heterogeneous organ. Beside the heterogeneity associated
to different tissue types (white, brown, and 'brite') and its location-related heterogeneity …

Recent studies suggest that, even within a single adipose depot, there may be distinct
subpopulations of adipocytes. To investigate this cellular heterogeneity, we have developed …

Type 1 diabetes is a chronic autoimmune disease which results in inefficient regulation of
glucose homeostasis and can lead to different vascular comorbidities through life. In this …

The epidemic of obesity is recognized as one of the most important public health problems
facing the world today. According to 2014 World Health Organization (WHO) data, 1 39% of …

Objective/methods DNA methylation plays an important role in obesity and related metabolic
complications. We examined genome-wide DNA promoter methylation along with mRNA …

MicroRNAs (miRNAs) are important post-transcriptional regulators involved in animal
adipogenesis, however, their roles in bovine fat deposition remain poorly understood. In the …

Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC) are organosulfur
phytochemicals rich in cruciferous vegetables. We investigated the antiobesity and …

Obesity is associated with metabolic disorders such as insulin resistance and type 2
diabetes mellitus (T2DM), further increasing an already heightened cardiovascular risk …

(1) Background: Obesity and mood disorders are considered as the most prevalent
morbidities in many countries. We suppose that epigenetic mechanisms may induce higher …