[HTML][HTML] The changing epidemiology of fungal infections

C Lass-Flörl, S Steixner - Molecular Aspects of Medicine, 2023 - Elsevier
Invasive fungal diseases are common complications in critically ill patients and in those with
significant underlying imbalanced immune systems. Fungal co-, and/or super-infections are …

Triazole antifungal agents in invasive fungal infections: a comparative review

C Lass-Flörl - Drugs, 2011 - Springer
Invasive fungal disease continues to be a problem associated with significant morbidity and
high mortality in immunocompromised and, to a lesser extent, immunocompetent …

Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options

JCO Sardi, DR Silva, MJS Mendes-Giannini… - Microbial …, 2018 - Elsevier
Candida auris emerged as a pathogen resistant to multiple antifungal and has been
associated with nosocomial outbreaks with high transmission capacity between hospitalized …

Targeting the fungal cell wall: current therapies and implications for development of alternative antifungal agents

S Hasim, JJ Coleman - Future medicinal chemistry, 2019 - Taylor & Francis
Fungal infections are a worldwide problem associated with high morbidity and mortality.
There are relatively few antifungal agents, and resistance has emerged within these …

[HTML][HTML] Bench-to-bedside review: Rapid molecular diagnostics for bloodstream infection-a new frontier?

A Afshari, J Schrenzel, M Ieven, S Harbarth - Critical care, 2012 - Springer
Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge.
Current standard bacterial identification based on blood culture platforms is intrinsically time …

Antifungal versus antibacterial defence of insect wings

EP Ivanova, DP Linklater, A Aburto-Medina, P Le… - Journal of Colloid and …, 2021 - Elsevier
Hypothesis: The ability exhibited by insect wings to resist microbial infestation is a unique
feature developed over 400 million years of evolution in response to lifestyle and …

The emerging epidemiology of mould infections in developing countries

A Chakrabarti, R Singh - Current opinion in infectious diseases, 2011 - journals.lww.com
Despite limited studies, certain peculiarities have been observed in invasive mould
infections in developing countries, including a high incidence of ophthalmic lesions …

[HTML][HTML] Biomimetic nanopillar silicon surfaces rupture fungal spores

DP Linklater, PH Le, A Aburto-Medina… - International Journal of …, 2023 - mdpi.com
The mechano-bactericidal action of nanostructured surfaces is well-documented; however,
synthetic nanostructured surfaces have not yet been explored for their antifungal properties …

Biological exploration of a novel 1, 2, 4-triazole-indole hybrid molecule as antifungal agent

F Pagniez, N Lebouvier, YM Na… - Journal of enzyme …, 2020 - Taylor & Francis
Abstract (2-(2, 4-Dichlorophenyl)-3-(1 H-indol-1-yl)-1-(1, 2, 4-1 H-triazol-1-yl) propan-2-ol (8
g), a new 1, 2, 4-triazole-indole hybrid molecule, showed a broad-spectrum activity against …

New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies

İS Doğan, S Sarac, S Sari, D Kart, ŞE Gökhan… - European journal of …, 2017 - Elsevier
Azole antifungals are potent inhibitors of fungal lanosterol 14α demethylase (CYP51) and
have been used for eradication of systemic candidiasis clinically. Herein we report the …