EDH: endothelium‐dependent hyperpolarization and microvascular signalling
CJ Garland, KA Dora - Acta Physiologica, 2017 - Wiley Online Library
Endothelium‐dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in
small resistance arteries and thus an important modulator of blood pressure and flow. As the …
small resistance arteries and thus an important modulator of blood pressure and flow. As the …
Endothelium‐dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?
TM Griffith - British journal of pharmacology, 2004 - Wiley Online Library
An endothelium‐derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO)
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …
Sympathetic and sensory-motor nerves in peripheral small arteries
Small arteries, which play important roles in controlling blood flow, blood pressure, and
capillary pressure, are under nervous influence. Their innervation is predominantly …
capillary pressure, are under nervous influence. Their innervation is predominantly …
Rhythmicity in arterial smooth muscle
RE Haddock, CE Hill - The Journal of physiology, 2005 - Wiley Online Library
Many arteries and arterioles exhibit rhythmical contractions which are synchronous over
considerable distances. This vasomotion is likely to assist in tissue perfusion especially …
considerable distances. This vasomotion is likely to assist in tissue perfusion especially …
Regulation of cellular communication by signaling microdomains in the blood vessel wall
It has become increasingly clear that the accumulation of proteins in specific regions of the
plasma membrane can facilitate cellular communication. These regions, termed signaling …
plasma membrane can facilitate cellular communication. These regions, termed signaling …
Rapid endothelial cell–selective loading of connexin 40 antibody blocks endothelium-derived hyperpolarizing factor dilation in rat small mesenteric arteries
In resistance arteries, spread of hyperpolarization from the endothelium to the adjacent
smooth muscle is suggested to be a crucial component of dilation resulting from …
smooth muscle is suggested to be a crucial component of dilation resulting from …
Voltage-dependent Ca2+ entry into smooth muscle during contraction promotes endothelium-mediated feedback vasodilation in arterioles
Vascular smooth muscle contraction is suppressed by feedback dilation mediated by the
endothelium. In skeletal muscle arterioles, this feedback can be activated by Ca2+ signals …
endothelium. In skeletal muscle arterioles, this feedback can be activated by Ca2+ signals …
Integrated Ca2+ Signaling Between Smooth Muscle and Endothelium of Resistance Vessels
Y Yashiro, BR Duling - Circulation research, 2000 - Am Heart Assoc
Cell-cell communication in the arteriolar wall was examined using the Ca2+-sensitive
indicator fura-2 and the Ca2+ buffer BAPTA as means of measuring and buffering cellular …
indicator fura-2 and the Ca2+ buffer BAPTA as means of measuring and buffering cellular …
Local regulation of microvascular perfusion
Publisher Summary This chapter discusses the local control of microvascular perfusion,
which has been described as “the maintenance of appropriate tissue blood flow despite …
which has been described as “the maintenance of appropriate tissue blood flow despite …
Endothelium-dependent hyperpolarization: the evolution of myoendothelial microdomains
CJ Garland, KA Dora - Journal of Cardiovascular Pharmacology, 2021 - journals.lww.com
Endothelium-derived hyperpolarizing factor (EDHF) was envisaged as a chemical entity
causing vasodilation by hyperpolarizing vascular smooth muscle (VSM) cells and distinct …
causing vasodilation by hyperpolarizing vascular smooth muscle (VSM) cells and distinct …