4 (3H)-Quinazolinone derivatives: Promising antibacterial drug leads
Emergence of drug resistance has created unmet medical need for the development of new
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …
Synthesis of 1, 2, 3-triazole linked 4 (3H)-Quinazolinones as potent antibacterial agents against multidrug-resistant Staphylococcus aureus
Methicillin and vancomycin resistant Staphylococcus aureus infections are an emerging
global health concern leading to increasing morbidity and mortality. Continuous increase in …
global health concern leading to increasing morbidity and mortality. Continuous increase in …
A literature review on pharmacological aspects, docking studies, and synthetic approaches of quinazoline and quinazolinone derivatives
MM Ghoneim, MA Abdelgawad… - Archiv der …, 2024 - Wiley Online Library
Quinazoline and quinazolinone derivatives piqued medicinal chemistry interest in
developing novel drug candidates owing to their pharmacological potential. They are …
developing novel drug candidates owing to their pharmacological potential. They are …
Ultrasound mediated efficient synthesis of new 4-oxoquinazolin-3 (4H)-yl) furan-2-carboxamides as potent tyrosinase inhibitors: Mechanistic approach through …
We have carried out the synthesis of new 4-oxoquinazolin-3 (4H)-yl) furan-2-carboxamide
derivatives by the reaction between isatoic anhydride, 2-furoic hydrazide and substituted …
derivatives by the reaction between isatoic anhydride, 2-furoic hydrazide and substituted …
Synthesis and evaluation of new 4 (3H)-Quinazolinone derivatives as potential anticancer agents
A series of new 4 (3H)-quinazolinones were synthesized and evaluated for their cytotoxic
activity against a set of human cancer cell lines MDA-MB-231 and MCF-7 (breast), HCT-116 …
activity against a set of human cancer cell lines MDA-MB-231 and MCF-7 (breast), HCT-116 …
[PDF][PDF] Aj csian ournalof hemistry aj csian ournalof hemistry
Novel thiazolidine-2, 4-dione (TZD) based pyrimidine derivatives have been synthesized by
Knoevenagel condensation reaction between thiazolidine-2, 4-dione and amino pyrimidinyl …
Knoevenagel condensation reaction between thiazolidine-2, 4-dione and amino pyrimidinyl …
Synthesis and evaluation of new quinazolin-4 (3H)-one derivatives as potent antibacterial agents against multidrug resistant Staphylococcus aureus and …
Staphylococcus aureus and Mycobacterium tuberculosis are major causative agents
responsible for serious nosocomial and community-acquired infections impacting healthcare …
responsible for serious nosocomial and community-acquired infections impacting healthcare …
Synthesis and evaluation of new 4-oxoquinazolin-3 (4H)-yl) benzoic acid and benzamide derivatives as potent antibacterial agents effective against multidrug …
Abstract Treatment of nosocomial and community acquired Staphylococcus aureus
infections has become more challenging due to the egression of multi-drug resistance. This …
infections has become more challenging due to the egression of multi-drug resistance. This …
Palladium-catalyzed cascade reactions in aqueous media: synthesis and photophysical properties of pyrazino-fused quinazolinones
Y Zhang, W Xiong, L Chen, Y Shao, R Li… - Organic Chemistry …, 2021 - pubs.rsc.org
Heterocycle-fused quinazolinone derivatives have attracted great attention due to their
diversified biological and optical activities. In this study, a novel one-pot palladium-catalyzed …
diversified biological and optical activities. In this study, a novel one-pot palladium-catalyzed …
[HTML][HTML] One pot synthesis of 5-hydroxyalkylated thiadiazine thiones: Implication in pain management and bactericidal properties
The synthesis of a new series of thiadiazine thiones including 5-(2-hydroxyethyl)-3-alkyl/aryl-
1, 3, 5-thiadiazine-2-thiones (1–5), 5-(2-hydroxypropyl)-3-alkyl/aryl-1, 3, 5-thiadiazine-2 …
1, 3, 5-thiadiazine-2-thiones (1–5), 5-(2-hydroxypropyl)-3-alkyl/aryl-1, 3, 5-thiadiazine-2 …