Many biological tissues offer J-shaped stress–strain responses, since their microstructures
exhibit a three-dimensional (3D) network construction of curvy filamentary structures that …

Detailed clinical assessment of corneal biomechanics has the potential to revolutionize the
ophthalmic industry through enabling quicker and more proficient diagnosis of corneal …

Collagen fibrils are the building blocks of many tissues from fish scales and tendons to bone.
Synchrotron small-angle X-ray scattering (SAXS) with in situ mechanical testing is a …

The cornea provides the largest refractive power for the human visual system. Its stiffness,
along with intraocular pressure (IOP), are linked to several pathologies, including …

Type II collagen fibril diameters in cartilage are beneath the diffraction limit of optical
microscopy, which makes the assessment of collagen organization very challenging. In this …

Purpose To introduce a new method to map the mechanical stiffness of healthy and
keratoconic corneas. Methods Numerical modeling based on the finite element method was …

The process of mineralization fundamentally alters collagenous tissue biomechanics. While
the structure and organization of mineral particles have been widely studied, the impact of …

Biomechanical changes to the collagen fibrillar architecture in articular cartilage are
believed to play a crucial role in enabling normal joint function. However, experimentally …

The purpose of this study was to develop a novel non-contact optical coherence
elastography (OCE) approach to measure laterally and axially highly resolved corneal strain …

Background To investigate the new cornea biomechanical parameter stress-strain index
(SSI) in Chinese healthy people and the factors associated with SSI. Methods A total of 175 …