It has been nearly three decades since the budding yeast Saccharomyces cerevisiae
became a significant model organism for aging research and it has emerged as both simple …

Carefully maintained and precisely inherited chromosomal DNA provides long-term genetic
stability, but eukaryotic cells facing environmental challenges can benefit from the …

Asymmetric partitioning of fate determinants is a mechanism that contributes to T cell
differentiation. However, it remains unclear whether the ability of T cells to divide …

The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and
cytoplasm, and in many species, it changes composition as the organism ages. However …

In the plasma membrane and in synthetic membranes, resident lipids may laterally unmix to
form domains of distinct biophysical properties. Whether lipids also drive the lateral …

Fluorescent nanodiamonds are frequently used as biolabels. They have also recently been
established for magnetic resonance and temperature sensing at the nanoscale level. To …

Efficient immune responses rely on heterogeneity, which in CD8+ T cells, amongst other
mechanisms, is achieved by asymmetric cell division (ACD). Here we find that ageing …

As in human cells, yeast telomeres can be maintained in cells lacking telomerase activity by
recombination‐based mechanisms known as ALT (Alternative Lengthening of Telomeres). A …

The target of rapamycin (TOR) pathway is an evolutionarily conserved signal transduction
system that governs a plethora of eukaryotic biological processes, but its role in …

Eukaryotic cells are subdivided into membrane-bound compartments specialized in different
cellular functions and requiring dedicated sets of proteins. Although cells developed …