Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …

Numerous studies have shown that non-coding RNAs play crucial roles in the development
and progression of various tumor cells. Plasmacytoma variant translocation 1 (PVT1) mainly …

Background Previous molecular subtyping for bladder carcinoma (BLCA) involved< 450
samples, with diverse classifications. Objective To identify molecular subtypes by curating a …

Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and
genetically heterogeneous malignancies, characterized by distinct prognoses based upon …

Gene editing has great potential in treating diseases caused by well-characterized
molecular alterations. The introduction of clustered regularly interspaced short palindromic …

Objectives To evaluate variant histologies (VHs) for disease‐specific survival (DSS) in
patients with invasive urothelial bladder cancer (BCa) undergoing radical cystectomy (RC) …

Bladder cancer (BC) is a heterogeneous disease from a molecular, morphological, and
clinical standpoint. HER2 is a known oncogene involved in bladder carcinogenesis …

Purpose: Neuroendocrine (NE) bladder carcinoma is a rare and aggressive variant.
Molecular subtyping studies have found that 5% to 15% of muscle-invasive bladder cancer …

Poorly differentiated neuroendocrine carcinomas (PD-NEC) are rare cancers garnering
interest as they become more commonly encountered in the clinic. This is due to improved …

Cancer is a genetic disease stemming from genetic and epigenetic mutations and is the
second most common cause of death across the globe. Clustered regularly interspaced …