Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by
gasdermin D (GSDMD)-mediated membrane pore formation, cell swelling and rapid lysis …

Pyroptosis is a form of programmed cell death activated by various stimuli and is
characterized by inflammasome assembly, membrane pore formation, and the secretion of …

The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2) has overwhelmed healthcare systems requiring the rapid development of …

Pyroptosis is a kind of pro-inflammatory cell death. Compared with autophagy and
apoptosis, pyroptosis has unique characteristics in morphology and mechanism …

During cardiac reperfusion after myocardial infarction, the heart is subjected to cascading
cycles of ischaemia reperfusion injury (IRI). Patients presenting with this injury succumb to …

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common respiratory
critical syndrome that currently has no effective therapeutic interventions. Pulmonary …

Microglia are the primary innate immune system cells in the central nervous system (CNS).
They are crucial for the immunity, neurogenesis, synaptogenesis, neurotrophic support …

Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by
gasdermin protein-mediated membrane pore formation, cell swelling, and rapid lysis …

NLRP3 inflammasome is an intracellular protein complex that initiates cellular injury via
assembly of NLRP3, ASC and caspase-1 in response to microbial infection and sterile …

Alcoholism is one of the most common diseases that can lead to the development of several
chronic diseases including steatosis, and cognitive dysfunction. Statins are lipid-lowering …