The pathogenicity of L. pneumophila, the causative agent of Legionnaires' disease, depends
on an arsenal of interacting proteins. Here we describe how surface-associated and …

Legionella pneumophila is the causative agent of Legionnaires' disease, a serious form of
pneumonia. Its macrophage infectivity potentiator (Mip), a member of a highly conserved …

cancer, neurodegeneration, psychiatric disorders, bacterial and viral infections (Lee et al.,
2011; Blair et al., 2015; Ünal and Steinert, 2014), while bacterial PPIases are involved in …

LpMip inhibitors known so far. Selected compounds were nontoxic to human cells, displayed
antibacterial activity and block bacterial proliferation in cellular infection-assays as well as …

Vacuolar pathogens reside and replicate within host-derived, membrane-bound,
intracellular compartments that protect the pathogen from cytosolic host defenses. Loss of …

Legionella pneumophila (Lp) is a common etiological agent of bacterial pneumonia that
causes Legionnaires' disease (LD). The bacterial membrane-associated virulence factor …