Genome-wide association studies (GWAS) have now correlated hundreds of genetic
variants with complex genetic diseases and drug efficacy. Functional characterization of …

Celiac disease (CeD) is a multifactorial autoimmune disorder spread worldwide. The
exposure to gluten, a protein found in cereals like wheat, barley and rye, is the main …

Abstract Transglutaminase 2 (TG2) plays a pivotal role in the pathogenesis of celiac disease
(CeD) by deamidating dietary gluten peptides, which facilitates antigenic presentation and a …

Celiac disease is an autoimmune disorder in which ingestion of dietary gluten triggers an
immune reaction in the small intestine leading to destruction of the lining epithelium. Current …

Background & Aims Celiac disease (CeD), an immune-mediated disease with enteropathy
triggered by gluten, affects~ 1% of the general European population. Currently, there are no …

The prevalence of celiac disease increased in recent years. In addition to the genetic and
immunological factors, it appears that environmental determinants are also involved in the …

Abstract Background Celiac disease (CeD) is an immune-mediated disorder that develops
in genetically predisposed individuals upon gluten consumption. HLA risk alleles explain …

Celiac Disease (CeD) is a complex immune disorder involving villous atrophy in the small
intestine that is triggered by gluten intake. Current CeD diagnosis is based on late-stage …

The identification of the dwarf phenotype in chicken is based on body weight, height, and
shank length, leaving the differentiation between dwarf and small breeds ambiguous. The …

Abstract Background Celiac disease (CeD) is a primary malabsorption syndrome with no
specific therapy, which greatly affects the quality of life. Since the pathogenesis of CeD …