Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …

Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Animal studies are now showing the exciting potential to achieve significant functional
recovery following central nervous system (CNS) injury by manipulating both the inefficient …

Our brain serves as a center for cognitive function and neurons within the brain relay and
store information about our surroundings and experiences. Modulation of this complex …

Stem cell therapies are being explored extensively as treatments for degenerative eye
disease, either for replacing lost neurons, restoring neural circuits or, based on more recent …

Recovery from traumatic spinal cord injury (SCI) usually fails due to a cascade of cellular
and molecular events that compromise neural tissue reconstitution by giving rise to glial …

The chronic, excessive consumption of alcohol results in significant modification of selective
neural systems of the brain structure, physiology, and function. Quantitative MR structural …

Chondroitin sulfate proteoglycans are the principal inhibitory component of glial scars, which
form after damage to the adult central nervous system and act as a barrier to regenerating …

Peripheral nerve injury may result in injury without gaps or injury with gaps between nerve
stumps. In the presence of a nerve defect, the placement of an autologous nerve graft is the …

Stroke induces axonal sprouting in peri-infarct cortex. A set of growth-associated genes
important in axonal sprouting in peripheral nervous system regeneration and cortical …