A major problem of neurobiology concerns the failure of injured mammalian spinal cord to
repair itself. This review summarizes work done on two preparations in which regeneration …

The strategic importance of the genome sequence of the gray, short-tailed opossum,
Monodelphis domestica, accrues from both the unique phylogenetic position of metatherian …

Primary dissociated neuronal cultures have become a standard model for studying central
nervous system (CNS) development. Such cultures are predominantly prepared from the …

Activating transcription factor 3 (ATF3), a member of the ATF/cAMP response element-
binding (CREB) family, is upregulated by various intracellular and extracellular signals such …

Female laboratory opossums of some genetic stocks can reach sexual maturity as early as
five months of age, and males achieve sexual maturity two to three weeks later …

Methods for reliable evaluation of spinal cord (SC) injury in rats at short periods (2 and 24 h)
after lesion were tested to characterize the mechanisms implicated in primary SC damage …

This study describes a combined transcriptome and proteome analysis of Monodelphis
domestica response to spinal cord injury at two different postnatal ages. Previously we …

Neurodegenerative diseases are one of the greatest medical burdens of the modern age,
being mostly incurable and with limited prognostic and diagnostic tools. Amyotrophic lateral …

Evolutionary studies have long emphasized that the genetic architecture of traits holds
important microevolutionary consequences. Yet, studies comparing the genetic architecture …

One of the major challenges of modern neurobiology concerns the inability of the adult
mammalian central nervous system (CNS) to regenerate and repair itself after injury. It is still …