Pseudomonas aeruginosa and microbial keratitis

Y Hilliam, S Kaye, C Winstanley - Journal of medical …, 2020 - microbiologyresearch.org
Pseudomonas aeruginosa, a versatile Gram-negative pathogen that can cause a wide
range of infections, is the most common causative agent in cases of bacterial keratitis …

Inflammation: A Double-Edged Sword in the Response to Pseudomonas aeruginosa Infection

CK Lin, BI Kazmierczak - Journal of innate immunity, 2017 - karger.com
The Gram-negative opportunistic pathogen Pseudomonas aeruginosa exploits failures of
barrier defense and innate immunity to cause acute infections at a range of anatomic sites …

[HTML][HTML] Nucleoside diphosphate kinase (Ndk): a pleiotropic effector manipulating bacterial virulence and adaptive responses

H Yu, X Rao, K Zhang - Microbiological research, 2017 - Elsevier
Nucleoside diphosphate kinase (Ndk) is a housekeeping enzyme that balances cellular
nucleoside triphosphate (NTP) pools by catalyzing the reversible transfer of γ-phosphate …

Molecular and structural basis of nucleoside diphosphate kinase–mediated regulation of spore and sclerotia development in the fungus Aspergillus flavus

Y Wang, S Wang, X Nie, K Yang, P Xu, X Wang… - Journal of Biological …, 2019 - ASBMB
The fundamental biological function of nucleoside diphosphate kinase (NDK) is to catalyze
the reversible exchange of the γ-phosphate between nucleoside triphosphate (NTP) and …

Exoproteomics for Better Understanding Pseudomonas aeruginosa Virulence

S Sauvage, J Hardouin - Toxins, 2020 - mdpi.com
Pseudomonas aeruginosa is the most common human opportunistic pathogen associated
with nosocomial diseases. In 2017, the World Health Organization has classified P …

A novel kinase function of a nucleoside‐diphosphate‐kinase homologue in Porphyromonas gingivalis is critical in subversion of host cell apoptosis by targeting heat …

J Lee, JAS Roberts, KR Atanasova… - Cellular …, 2018 - Wiley Online Library
We have previously shown that a homologue of a conserved nucleoside‐diphosphate‐
kinase (Ndk) family of multifunctional enzymes and secreted molecule in Porphyromonas …

Unraveling modulation effects on albumin synthesis and inflammation by Striatin, a bioactive protein fraction isolated from Channa striata: In silico proteomics and in …

A Musliha, D Dermawan, P Rahayu, RR Tjandrawinata - Heliyon, 2024 - cell.com
Hypoalbuminemia, associated with inflammation in severely ill patients, can emerge due to
decreased albumin production. Transforming growth factor-beta (TGF-β) and nuclear factor …

[HTML][HTML] Purinergic signaling during Porphyromonas gingivalis infection

CLC Almeida-da-Silva, AC Morandini, H Ulrich… - biomedical …, 2016 - Elsevier
Despite recent advances unraveling mechanisms of host–pathogen interactions in innate
immunity, the participation of purinergic signaling in infection-driven inflammation remains …

The Pseudomonas aeruginosa HSP70-like protein DnaK induces IL-1β expression via TLR4-dependent activation of the NF-κB and JNK signaling pathways

JH Lee, J Jeon, F Bai, S Jin, W Wu, UH Ha - … Immunology, Microbiology and …, 2019 - Elsevier
IL-1β expression is increased in response to P. aeruginosa infection, but the responsible
proteins have not been clearly elucidated. Here, we demonstrate for the first time that IL-1β …

Ndk, a novel host-responsive regulator, negatively regulates bacterial virulence through quorum sensing in Pseudomonas aeruginosa

H Yu, J Xiong, R Zhang, X Hu, J Qiu, D Zhang, X Xu… - Scientific reports, 2016 - nature.com
Pathogenic bacteria could adjust gene expression to enable their survival in the distinct host
environment. However, the mechanism by which bacteria adapt to the host environment is …