The functions, purposes, and roles of metallothioneins have been the subject of
speculations since the discovery of the protein over 60 years ago. This article guides …

Recent discoveries in zinc biology provide a new platform for discussing the primary
physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc …

Covering: 1999 to 2009 Metallothioneins have been the subject of intense study for five
decades, and have greatly inspired the development of bio-analytical methodologies …

Bacterial metallothioneins (MTs) have been known since the mid-1980s. The only family
known until recently was the BmtA family, exemplified by the zinc-and cadmium-binding …

Between 5 and 10% of all proteins of a given organism are estimated to require zinc for
function, and hence zinc is essential for almost any given metabolic process. It is therefore of …

Mammalian metallothioneins (MTs) are small cysteine-rich proteins whose primary role is
participation in zinc and copper homeostasis. Ever since their discovery, MTs have been …

Zn2+ is a necessary cofactor for thousands of mammalian proteins. Research has
suggested that transient fluxes of cellular Zn2+ are also involved in processes such as …

Abstract Metallothioneins (MTs), small cysteine-rich proteins, present in four major isoforms,
are key proteins involved in zinc and copper homeostasis in mammals. To date, only one X …

The small, cysteine-rich metallothionein family of proteins is currently considered to play a
critical role in the provision of metals to metalloenzymes. However, there is limited …

Mammalian metallothioneins (MTs) are small Cys-rich proteins involved in Zn (II) and Cu (I)
homeostasis. They bind seven Zn (II) ions in two distinct β-and α-domains, forming Zn3Cys9 …