Starvation Responses Throughout the Caenorhabditis  elegans Life Cycle

LR Baugh, PJ Hu - Genetics, 2020 - academic.oup.com
Caenorhabditis elegans survives on ephemeral food sources in the wild, and the species
has a variety of adaptive responses to starvation. These features of its life history make the …

[HTML][HTML] Epigenetic regulation of metabolism and inflammation by calorie restriction

D Hernández-Saavedra, L Moody, GB Xu, H Chen… - Advances in …, 2019 - Elsevier
Chronic caloric restriction (CR) without malnutrition is known to affect different cellular
processes such as stem cell function, cell senescence, inflammation, and metabolism …

Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response

S Luo, F He, J Luo, S Dou, Y Wang… - Nucleic acids …, 2018 - academic.oup.com
Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of small RNAs, yet their
regulatory roles have not been well understood. Here we studied the molecular mechanisms …

Caenorhabditis elegans respond to high-glucose diets through a network of stress-responsive transcription factors

J Alcántar-Fernández, RE Navarro… - PloS one, 2018 - journals.plos.org
High-glycemic-index diets, as well as a sedentary lifestyle are considered as determinant
factors for the development of obesity, type 2 diabetes, and cardiovascular diseases in …

MicroRNA mir-34 provides robustness to environmental stress response via the DAF-16 network in C. elegans

M Isik, TK Blackwell, E Berezikov - Scientific reports, 2016 - nature.com
Diverse stresses and aging alter expression levels of microRNAs, suggesting a role for
these posttranscriptional regulators of gene expression in stress modulation and longevity …

miRCat2: accurate prediction of plant and animal microRNAs from next-generation sequencing datasets

C Paicu, I Mohorianu, M Stocks, P Xu, A Coince… - …, 2017 - academic.oup.com
Motivation MicroRNAs are a class of∼ 21–22 nt small RNAs which are excised from a stable
hairpin-like secondary structure. They have important gene regulatory functions and are …

Time-restricted eating regimen differentially affects circulatory mirna expression in older overweight adults

SK Saini, A Singh, M Saini, M Gonzalez-Freire… - Nutrients, 2022 - mdpi.com
Time-restricted eating (TRE), a popular form of intermittent fasting, has been demonstrated
to provide multiple health benefits, including an extension of healthy lifespan in preclinical …

[HTML][HTML] Alternative models for transgenerational epigenetic inheritance: Molecular psychiatry beyond mice and man

GR Hime, SLA Stonehouse, TY Pang - World journal of psychiatry, 2021 - ncbi.nlm.nih.gov
Mental illness remains the greatest chronic health burden globally with few in-roads having
been made despite significant advances in genomic knowledge in recent decades. The field …

Characterization and expression profiling of microRNAs in response to plant feeding in two host-plant strains of the lepidopteran pest Spodoptera frugiperda

Y Moné, S Nhim, S Gimenez, F Legeai, I Seninet… - BMC genomics, 2018 - Springer
Background A change in the environment may impair development or survival of living
organisms leading them to adapt to the change. The resulting adaptation trait may reverse …

The microRNA machinery regulates fasting-induced changes in gene expression and longevity in Caenorhabditis elegans

A Kogure, M Uno, T Ikeda, E Nishida - Journal of Biological Chemistry, 2017 - ASBMB
Intermittent fasting (IF) is a dietary restriction regimen that extends the lifespans of
Caenorhabditis elegans and mammals by inducing changes in gene expression. However …